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dc.contributor.authorKurl, Sudhir
dc.contributor.authorJae, Sae Young
dc.contributor.authorMäkikallio, Timo H.
dc.contributor.authorVoutilainen, Ari
dc.contributor.authorHagnäs, Magnus J.
dc.contributor.authorKauhanen, Jussi
dc.contributor.authorLaukkanen, Jari A.
dc.date.accessioned2020-02-26T11:06:47Z
dc.date.available2020-02-26T11:06:47Z
dc.date.issued2020
dc.identifier.citationKurl, Sudhir; Jae, Sae Young; Mäkikallio, Timo H.; Voutilainen, Ari; Hagnäs, Magnus J.; Kauhanen, Jussi; Laukkanen, Jari A. (2020). Exercise cardiac power and the risk of heart failure in men : A population-based follow-up study. Journal of Sport and Health Science, Early online. DOI: 10.1016/j.jshs.2020.02.008
dc.identifier.otherCONVID_34737976
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/67979
dc.description.abstractBackground Little is known about exercise cardiac power (ECP), defined as the ratio of directly measured maximal oxygen uptake with peak systolic blood pressure during exercise on heart failure (HF) risk. We examined the association of ECP and the risk of HF. Methods This was a population-based cohort study of 2351 men from eastern Finland. The average time to follow-up was 25 years. Participants participated at baseline in an exercise stress test. A total of 313 cases of HF occurred. Results Men with low ECP (<9.84 mL/mmHg, lowest quartile) had a 2.37-fold (95% confidence interval (CI): 1.68 − 3.35, p < 0.0001) hazards ratio of HF as compared with men with high ECP (>13.92 mL/mmHg, highest quartile), after adjusting for age. Low ECP was associated with a 1.96-fold risk (95%CI: 1.38 − 2.78, p < 0.001) of HF after additional adjustment for conventional risk factors. After further adjustment for left ventricular hypertrophy, the results hardly changed (hazards ratio = 1.87, 95%CI: 1.31 − 2.66, p < 0.001). One SD increase in ECP (3.16 mL/mmHg) was associated with a decreased risk of HF by 28% (95%CI: 17% − 37%). Conclusion ECP provides a non-invasive and easily available measure from cardiopulmonary exercise test in predicting HF. However, ECP did not provide additional value over maximal oxygen uptake.en
dc.format.mimetypeapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.relation.ispartofseriesJournal of Sport and Health Science
dc.rightsCC BY-NC-ND 4.0
dc.subject.otherexercise cardiac power
dc.subject.otherheart failure
dc.subject.othermen
dc.titleExercise cardiac power and the risk of heart failure in men : A population-based follow-up study
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202002262206
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.description.reviewstatuspeerReviewed
dc.relation.issn2095-2546
dc.relation.volumeEarly online
dc.type.versionacceptedVersion
dc.rights.copyright© 2020 Published by Elsevier B.V. on behalf of Shanghai University of Sport
dc.rights.accesslevelopenAccessfi
dc.subject.ysoliikunta
dc.subject.ysomaksimaalinen hapenotto
dc.subject.ysosydän
dc.subject.ysofyysinen aktiivisuus
dc.subject.ysosydämen vajaatoiminta
dc.subject.ysomiehet
dc.subject.ysosydän- ja verisuonitaudit
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p916
jyx.subject.urihttp://www.yso.fi/onto/yso/p25454
jyx.subject.urihttp://www.yso.fi/onto/yso/p16731
jyx.subject.urihttp://www.yso.fi/onto/yso/p23102
jyx.subject.urihttp://www.yso.fi/onto/yso/p18795
jyx.subject.urihttp://www.yso.fi/onto/yso/p8173
jyx.subject.urihttp://www.yso.fi/onto/yso/p9886
dc.rights.urlhttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.relation.doi10.1016/j.jshs.2020.02.008


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