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dc.contributor.authorWalker, S.
dc.contributor.authorHäkkinen, K.
dc.contributor.authorNewton, R. U.
dc.contributor.authorMarkworth, J. F.
dc.contributor.authorPundir, S.
dc.contributor.authorHaff, G. G.
dc.contributor.authorCameron-Smith, D.
dc.contributor.authorBlazevich, A. J.
dc.date.accessioned2020-01-03T09:57:16Z
dc.date.available2020-01-03T09:57:16Z
dc.date.issued2020
dc.identifier.citationWalker, S., Häkkinen, K., Newton, R. U., Markworth, J. F., Pundir, S., Haff, G.G., Cameron-Smith, D., & Blazevich, A. J. (2020). Acute responses of comprehensive gonadosteroids and corticosteroids to resistance exercise before and after 10 weeks of supervised strength training. <i>Experimental Physiology</i>, <i>105</i>(3), 438-448. <a href="https://doi.org/10.1113/EP087995" target="_blank">https://doi.org/10.1113/EP087995</a>
dc.identifier.otherCONVID_33910382
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/67084
dc.description.abstractResistance training is a potent stimulus for muscle growth and steroid hormones are known to play a role in this adaptation. However, very little is known about the acute exercise‐induced gonadosteroid and corticosteroid hormone responses, including key smaller‐concentration intermediate hormones. The present study determined the acute responses of these steroid hormone families using quantitative UHPLC mass spectrometry (MS) following resistance exercise in strength‐trained men. Venous and fingertip blood was drawn pre‐, mid‐, 5 min post‐ and 15 min post‐resistance exercise, both before and after 10 weeks of supervised resistance training. The experimental resistance exercise sessions consisted of 3 sets of 10 repetitions in the bilateral leg press and 3 sets of 10 repetitions in the unilateral knee extension with 2 and 1 min recovery between sets, respectively. Statistically significant (P < 0.05) increases in the concentration of hormones in the gonadosteroid (including; dehydroepiandrosterone (DHEA), androstenedione, testosterone, estrone) and the corticosteroid (including; cortisol, corticosterone and cortisone) families were demonstrated after both experimental resistance exercise sessions, irrespective of training status. Correlation analyses revealed relationships between: 1) DHEA and androstenedione, 2) DHEA and cortisol, 3) androstenedione and estrone, and 4) 11‐deoxycortisol and cortisol. Testosterone appears to acutely increase independently of other intermediary hormones following resistance exercise. In conclusion, smaller‐concentration intermediary gonadosteroids (e.g. estrone) and corticosteroids (e.g. corticosterone) respond robustly to resistance exercise in strength‐trained men, although it seems that testosterone concentrations are regulated by factors other than the availability of precursor hormones and changes in plasma volume.en
dc.format.mimetypeapplication/pdf
dc.languageeng
dc.language.isoeng
dc.publisherWiley-Blackwell Publishing Ltd.
dc.relation.ispartofseriesExperimental Physiology
dc.rightsIn Copyright
dc.subject.other11‐deoxycortisol
dc.subject.otherandrostenedione
dc.subject.othercortisol
dc.subject.otherDHEA
dc.subject.otherestrogen
dc.subject.otherhormones
dc.subject.othermass spectroscopy
dc.subject.otherresistance training
dc.subject.othertestosterone
dc.subject.otherUHPLC mass spectroscopy
dc.titleAcute responses of comprehensive gonadosteroids and corticosteroids to resistance exercise before and after 10 weeks of supervised strength training
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202001031018
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.contributor.oppiaineValmennus- ja testausoppifi
dc.contributor.oppiaineScience of Sport Coaching and Fitness Testingen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange438-448
dc.relation.issn0958-0670
dc.relation.numberinseries3
dc.relation.volume105
dc.type.versionacceptedVersion
dc.rights.copyright© 2019 The Authors, Experimental Physiology & The Physiological Society
dc.rights.accesslevelopenAccessfi
dc.subject.ysohormonit
dc.subject.ysotestosteroni
dc.subject.ysosteroidit
dc.subject.ysovoimaharjoittelu
dc.subject.ysohormonaaliset vaikutukset
dc.subject.ysomassaspektrometria
dc.subject.ysoestrogeenit
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p2589
jyx.subject.urihttp://www.yso.fi/onto/yso/p23240
jyx.subject.urihttp://www.yso.fi/onto/yso/p10983
jyx.subject.urihttp://www.yso.fi/onto/yso/p16233
jyx.subject.urihttp://www.yso.fi/onto/yso/p7701
jyx.subject.urihttp://www.yso.fi/onto/yso/p10755
jyx.subject.urihttp://www.yso.fi/onto/yso/p16792
dc.rights.urlhttp://rightsstatements.org/page/InC/1.0/?language=en
dc.relation.doi10.1113/EP087995
jyx.fundinginformationThis work was funded internally by CESSR, Edith Cowan University during data collection and by the Faculty of Sport and Health Sciences, University of Jyväskylä. Mass spectroscopy analysis costs were provided by Liggins Institute, The University of Auckland.
dc.type.okmA1


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