Older persons with signs of frailty in a home-based physical exercise intervention : baseline characteristics of an RCT
Suikkanen, S., Soukkio, P., Pitkälä, K., Kääriä, S., Kautiainen, H., Sipilä, S., Kukkonen-Harjula, K., & Hupli, M. (2019). Older persons with signs of frailty in a home-based physical exercise intervention : baseline characteristics of an RCT. Aging Clinical and Experimental Research, 31(10), 1419-1427. https://doi.org/10.1007/s40520-019-01180-z
Published inAging Clinical and Experimental Research
DisciplineGerontologia ja kansanterveysGerontologian tutkimuskeskusGerontology and Public HealthGerontology Research Center
© Springer Nature Switzerland AG 2019
Background Increasing the level of physical activity among persons with signs of frailty improves physical functioning. There is a lack of long-term supervised physical exercise intervention studies including a validated definition of frailty. Aims To present baseline characteristics of persons with signs of frailty participating in a randomized long-term home-based physical exercise trial (HIPFRA), and to study associations between the severity of frailty, functional independence and health-related quality-of-life (HRQoL). Methods Three hundred persons, ≥ 65 years old and with signs of frailty (assessed by Fried´s phenotype criteria) were recruited from South Karelia, Finland and randomized to a 12-month physiotherapist-supervised home-based physical exercise program (n = 150), and usual care (n = 150). Assessments at the participants’ homes at baseline, and after 3, 6 and 12 months included the Short Physical Performance Battery (SPPB), the Functional Independence Measure (FIM), HRQoL (15D) and the Mini-Mental State Examination (MMSE). Results Eligibility was screened among 520 persons; 300 met the inclusion criteria and were randomized. One person withdrew consent after randomization. A majority (75%) were women, 182 were pre-frail and 117 frail. The mean age was 82.5 (SD 6.3) years, SPPB 6.2 (2.6), FIM 108.8 (10.6) and MMSE 24.4 (3.1) points, with no significant differences between the study groups. Inverse associations between the severity of frailty vs. FIM scores and HRQoL (p < 0.001 for both) were found. Conclusions Our participants showed marked physical frailty without major disabilities. The severity of frailty seems to be associated with impaired functional independence and HRQoL. ...
PublisherSpringer International Publishing
ISSN Search the Publication Forum1594-0667
Publication in research information system
MetadataShow full item record
- Liikuntatieteiden tiedekunta 
Additional information about fundingThe HIPFRA study is funded by the South Karelia Social and Health Care District (Eksote, register number 1236/00.01.05.01/2013), by two governmental funding sources; The Social Insurance Institution of Finland (SII, register number 94/331/2013) and State Research Funding for Academic Health Research (Ministry of Social Affairs and Health), and by the Vyborg Foundation Against Tuberculosis. The funding bodies had no role in the design of the study, in collection, analysis and interpretation of the data, or in writing the manuscript. ...
Showing items with similar title or keywords.
Health-related Quality of Life of Breast Cancer Survivors Attending an Exercise Intervention Study : A Five-year Follow-up Roine, Eija; Sintonen, Harri; Kellokumpu-Lehtinen, Pirkko-Liisa; Penttinen, Heidi; Utriainen, Meri; Vehmanen, Leena; Huovinen, Riika; Kautiainen, Hannu; Nikander, Riku; Blomqvist, Carl; Saarto, Tiina (International Institute of Anticancer Research, 2020)Background/Aim: As the number of breast cancer survivors is increasing, their long-term health-related quality of life (HRQoL)has become an important issue. The aim of the study is to follow up the HRQoL of breast cancer ...
Investigating dose–response effects of multimodal exercise programs on health-related quality of life in older adults Kaushal, Navin; Langlois, Francis; Desjardins-Crépeau, Laurence; Hagger, Martin; Bherer, Louis (Dove Press, 2019)Background: Older adults are at risk of multiple chronic diseases, most of which could be prevented by engaging in regular physical activity. Frailty is a state of increased vulnerability to diseases. Worsening symptoms ...
Effects of Home-Based Physical Exercise on Days at Home and Cost-Effectiveness in Pre-Frail and Frail Persons : Randomized Controlled Trial Suikkanen, Sara A.; Soukkio, Paula K.; Aartolahti, Eeva M.; Kautiainen, Hannu; Kääriä, Sanna M.; Hupli, Markku T.; Sipilä, Sarianna; Pitkälä, Kaisu H.; Kukkonen-Harjula, Katriina T. (Elsevier BV, 2021)Objectives Frailty increases the risks of hospitalization, institutionalization, and death. Our objective was to study the effects of home-based physical exercise on the number of days spent at home among pre-frail and ...
Ten-year follow-up of health-related quality of life among ambulatory persons with multiple sclerosis at baseline Rintala, Aki; Häkkinen, Arja; Paltamaa, Jaana (Springer Netherlands; International Society for Quality of Life Studies, 2016)Purpose The aim of this 10-year follow-up study was to determine changes in health-related quality of life (HRQoL) over time among ambulatory persons with MS (PwMS) at the baseline using generic and disease-specific ...
Long-term health-related quality of life of breast cancer survivors remains impaired compared to the age-matched general population especially in young women : Results from the prospective controlled BREX exercise study Roine, Eija; Sintonen, Harri; Kellokumpu-Lehtinen, Pirkko-Liisa; Penttinen, Heidi; Utriainen, Meri; Vehmanen, Leena; Huovinen, Riikka; Kautiainen, Hannu; Nikander, Riku; Blomqvist, Carl; Hakamies-Blomqvist, Liisa; Saarto, Tiina (Elsevier, 2021)Objective To investigate long-term health-related quality of life (HRQoL) changes over time in younger compared to older disease-free breast cancer survivors who participated in a prospective randomized exercise ...