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dc.contributor.authorKorhonen, T.
dc.contributor.authorLatvala, A.
dc.contributor.authorDick, D.M.
dc.contributor.authorPulkkinen, Lea
dc.contributor.authorRose, R.J.
dc.contributor.authorKaprio, J.
dc.contributor.authorHuizink, A.C.
dc.date.accessioned2019-09-23T08:20:38Z
dc.date.available2019-09-23T08:20:38Z
dc.date.issued2012fi
dc.identifier.citationKorhonen, T., Latvala, A., Dick, D. M., Pulkkinen, L., Rose, R. J., Kaprio, J., & Huizink, A. C. (2012). Genetic and environmental influences underlying externalizing behaviors, cigarette smoking and illicit drug use across adolescence. <em>Behavior Genetics</em>, 42 (4), 614-625. <a href="https://doi.org/10.1007/s10519-012-9528-z">doi:10.1007/s10519-012-9528-z</a>fi
dc.identifier.otherTUTKAID_53388
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/65602
dc.description.abstractWe investigated genetic and environmental influences common to adolescent externalizing behavior (at age 12), smoking (at age 14) and initiation of drug use (at age 17) using the FinnTwin12 cohort data. Multivariate Cholesky models were fit to data from 737 monozygotic and 722 dizygotic twin pairs. Heritability of externalizing behavior was 56%, that of smoking initiation/amount 20/32%, and initiation of drug use 27%. In the best-fitting model common environmental influences explained most of the covariance between externalizing behavior and smoking initiation (69%) and amount (77%). Covariance between smoking initiation/amount and drug use was due to additive genetic (42/22%) and common environmental (58/78%) influences. Half of the covariance between externalizing behavior and drug use was due to shared genetic and half due to the environments shared by co-twins. Using a longitudinal, prospective design, our results indicate that early observed externalizing behavior provides significant underlying genetic and environmental influences common to later substance use, here manifested as initiation of drug use in late adolescence.fi
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofseriesBehavior Genetics
dc.rightsIn Copyright
dc.subject.otheradolescencefi
dc.subject.othercohort studiesfi
dc.subject.otherenvironmentfi
dc.subject.otherlongitudinal studiesfi
dc.subject.othersmokingfi
dc.titleGenetic and environmental influences underlying externalizing behaviors, cigarette smoking and illicit drug use across adolescencefi
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201909114126
dc.contributor.laitosPsykologian laitosfi
dc.contributor.laitosDepartment of Psychologyen
dc.contributor.oppiainePsykologia (ytk)
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2019-09-11T15:15:10Z
dc.description.reviewstatuspeerReviewed
dc.format.pagerange614-625
dc.relation.issn0001-8244
dc.relation.numberinseries4
dc.relation.volume42
dc.type.versionacceptedVersion
dc.rights.copyright© Springer Science+Business Media, LLC 2012
dc.rights.accesslevelopenAccessfi
dc.format.contentfulltext
dc.rights.urlhttp://rightsstatements.org/page/InC/1.0/?language=en
dc.relation.doi10.1007/s10519-012-9528-z


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