Organocatalytic Enantioselective Vinylogous Henry Reaction of 3,5-Dimethyl-4-nitroisoxazole with Trifluoromethyl Ketones

Jafari, Ehsan; Kundu, Dipti S.; Chauhan, Pankaj; Gajulapalli, V. Pratap Reddy; von Essen, Carolina; Rissanen, Kari; Enders, Dieter

doi:10.1055/s-0036-1590928

dc.contributor.author	Jafari, Ehsan
dc.contributor.author	Kundu, Dipti S.
dc.contributor.author	Chauhan, Pankaj
dc.contributor.author	Gajulapalli, V. Pratap Reddy
dc.contributor.author	von Essen, Carolina
dc.contributor.author	Rissanen, Kari
dc.contributor.author	Enders, Dieter
dc.date.accessioned	2018-06-04T08:26:02Z
dc.date.available	2018-09-04T21:35:30Z
dc.date.issued	2018
dc.identifier.citation	Jafari, E., Kundu, D. S., Chauhan, P., Gajulapalli, V. P. R., von Essen, C., Rissanen, K., & Enders, D. (2018). Organocatalytic Enantioselective Vinylogous Henry Reaction of 3,5-Dimethyl-4-nitroisoxazole with Trifluoromethyl Ketones. <i>Synthesis</i>, <i>50</i>(2), 323-329. <a href="https://doi.org/10.1055/s-0036-1590928" target="_blank">https://doi.org/10.1055/s-0036-1590928</a>
dc.identifier.other	CONVID_27278260
dc.identifier.other	TUTKAID_75299
dc.identifier.uri	https://jyx.jyu.fi/handle/123456789/58314
dc.description.abstract	The enantioselective vinylogous Henry reaction of 3,5-dimethyl-4-nitroisoxazole with trifluoromethyl ketones employing a bifunctional squaramide organocatalyst has been developed. A series of isoxazole bearing trifluoromethyl-substituted tertiary alcohols, 2-substituted (R)-1,1,1-trifluoro-3-(3-methyl-4-nitroisoxazol-5-yl)propan-2-ols, were obtained under these mild reaction conditions in good yields and moderate to good enantioselectivities.	fi
dc.format.mimetype	application/pdf
dc.language.iso	eng
dc.publisher	Georg Thieme Verlag
dc.relation.ispartofseries	Synthesis
dc.rights	In Copyright
dc.subject.other	asymmetric synthesis
dc.subject.other	isoxazole
dc.subject.other	trifluoromethyl ketone
dc.subject.other	squaramide organocatalyst
dc.subject.other	vinylogous Henry reaction
dc.title	Organocatalytic Enantioselective Vinylogous Henry Reaction of 3,5-Dimethyl-4-nitroisoxazole with Trifluoromethyl Ketones
dc.type	article
dc.identifier.urn	URN:NBN:fi:jyu-201805222701
dc.contributor.laitos	Kemian laitos	fi
dc.contributor.laitos	Department of Chemistry	en
dc.contributor.oppiaine	Orgaaninen kemia	fi
dc.contributor.oppiaine	Nanoscience Center	fi
dc.contributor.oppiaine	Organic Chemistry	en
dc.contributor.oppiaine	Nanoscience Center	en
dc.type.uri	http://purl.org/eprint/type/JournalArticle
dc.date.updated	2018-05-22T06:15:16Z
dc.type.coar	http://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatus	peerReviewed
dc.format.pagerange	323-329
dc.relation.issn	0039-7881
dc.relation.numberinseries	2
dc.relation.volume	50
dc.type.version	acceptedVersion
dc.rights.copyright	© Georg Thieme Verlag Stuttgart · New York, 2018.
dc.rights.accesslevel	openAccess	fi
dc.format.content	fulltext
dc.rights.url	http://rightsstatements.org/page/InC/1.0/?language=en
dc.relation.doi	10.1055/s-0036-1590928
dc.type.okm	A1

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