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dc.contributor.authorWen, Chenyu
dc.contributor.authorZeng, Shuangshuang
dc.contributor.authorArstila, Kai
dc.contributor.authorSajavaara, Timo
dc.contributor.authorZhu, Yu
dc.contributor.authorZhang, Zhen
dc.contributor.authorZhang, Shi-Li
dc.date.accessioned2017-03-08T06:57:41Z
dc.date.available2018-02-06T22:45:10Z
dc.date.issued2017
dc.identifier.citationWen, C., Zeng, S., Arstila, K., Sajavaara, T., Zhu, Y., Zhang, Z., & Zhang, S.-L. (2017). A generalized noise study of solid-state nanopores at low frequencies. <i>ACS Sensors</i>, <i>2</i>(2), 300-307. <a href="https://doi.org/10.1021/acssensors.6b00826" target="_blank">https://doi.org/10.1021/acssensors.6b00826</a>
dc.identifier.otherCONVID_26535292
dc.identifier.otherTUTKAID_72911
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/53209
dc.description.abstractNanopore technology has been extensively investigated for analysis of biomolecules, and a success story in this field concerns DNA sequencing using a nanopore chip featuring an array of hundreds of biological nanopores (BioNs). Solid-state nanopores (SSNs) have been explored to attain longer lifetime and higher integration density than what BioNs can offer, but SSNs are generally considered to generate higher noise whose origin remains to be confirmed. Here, we systematically study low-frequency (including thermal and flicker) noise characteristics of SSNs measuring 7 to 200 nm in diameter drilled through a 20-nm-thick SiNx membrane by focused ion milling. Both bulk and surface ionic currents in the nanopore are found to contribute to the flicker noise, with their respective contributions determined by salt concentration and pH in electrolytes as well as bias conditions. Increasing salt concentration at constant pH and voltage bias leads to increase in the bulk ionic current and noise therefrom. Changing pH at constant salt concentration and current bias results in variation of surface charge density, and hence alteration of surface ionic current and noise. In addition, the noise from Ag/AgCl electrodes can become predominant when the pore size is large and/or the salt concentration is high. Analysis of our comprehensive experimental results leads to the establishment of a generalized nanopore noise model. The model not only gives an excellent account of the experimental observations, but can also be used for evaluation of various noise components in much smaller nanopores currently not experimentally available.
dc.language.isoeng
dc.publisherAmerican Chemical Society
dc.relation.ispartofseriesACS Sensors
dc.subject.othersolid-state nanopores
dc.subject.othernanopore technology
dc.titleA generalized noise study of solid-state nanopores at low frequencies
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201702241517
dc.contributor.laitosFysiikan laitosfi
dc.contributor.laitosDepartment of Physicsen
dc.contributor.oppiaineKiihdytinlaboratoriofi
dc.contributor.oppiaineAccelerator Laboratoryen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2017-02-24T07:15:05Z
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange300-307
dc.relation.issn2379-3694
dc.relation.numberinseries2
dc.relation.volume2
dc.type.versionacceptedVersion
dc.rights.copyright© 2017 American Chemical Society. This is a final draft version of an article whose final and definitive form has been published by ACS. Published in this repository with the kind permission of the publisher.
dc.rights.accesslevelopenAccessfi
dc.subject.ysomelu
jyx.subject.urihttp://www.yso.fi/onto/yso/p1718
dc.relation.doi10.1021/acssensors.6b00826
dc.type.okmA1


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