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Body size at birth and coronary heart disease-related hospital care in adult men : Findings from the Helsinki Birth Cohort Study

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von Bonsdorff, M., von Bonsdorff, M., Martikainen, J., Salonen, M., Kajantie, E., Kautiainen, H., & Eriksson, J. G. (2017). Body size at birth and coronary heart disease-related hospital care in adult men : Findings from the Helsinki Birth Cohort Study. Annals of Medicine, 49 (2), 126-133. doi:10.1080/07853890.2016.1241426
Published in
Annals of Medicine
Authors
von Bonsdorff, Monika |
von Bonsdorff, Mikaela |
Martikainen, Janne |
Salonen, Minna |
Kajantie, Eero |
Kautiainen, Hannu |
Eriksson, Johan G.
Date
2017
Discipline
Gerontologia ja kansanterveys
Copyright
© 2016 Informa UK Limited, trading as Taylor & Francis Group. This is a final draft version of an article whose final and definitive form has been published by Taylor & Francis. Published in this repository with the kind permission of the publisher.

 
Aim: We investigated, among those who had been hospitalized at least once due to coronary heart disease (CHD), the relationship between ponderal index (PI, birthweight/length3) at birth, a measure of thinness, and the age at first hospitalization due to CHD, the number of CHD-related hospital care episodes, and cost of CHD-related hospital care from young adulthood to old age. Methods and results: Data from the Helsinki Birth Cohort Study included 964 men born in Helsinki, Finland during 1934–1944, who had been hospitalized due to CHD and had birth anthropometrics data. PI (kg/m3) was categorized into low (<25.0), medium (25.0–27.5), and high (>27.5). CHD-related hospital care data were available from 1971 to 2013. We observed an earlier onset of (p = .014 for linearity) and a higher rate of CHD-related hospital care episodes among those in the lowest PI group (incidence rate ratio: 1.35 [95% confidence interval: 1.16–1.59, p < .001]), compared to the highest PI group. CHD-related hospital care costs in the lowest PI group were 25% (p = .001, 4% to 46%) higher compared to those in the highest PI group. Discussion: Thinness at birth is associated with earlier onset, higher prevalence, and higher accumulated costs of CHD-related hospital in-patient care among men who developed CHD. ...
Publisher
Informa Healthcare ; Taylor & Francis Group; Finnish Medical Society Duodecim
ISSN Search the Publication Forum
0785-3890
Keywords
age of onset aging birthweight cardiovascular disease coronary heart disease
DOI
10.1080/07853890.2016.1241426
URI

http://urn.fi/URN:NBN:fi:jyu-201701261275

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