Body size at birth and coronary heart disease-related hospital care in adult men : Findings from the Helsinki Birth Cohort Study
von Bonsdorff, M., von Bonsdorff, M., Martikainen, J., Salonen, M., Kajantie, E., Kautiainen, H., & Eriksson, J. G. (2017). Body size at birth and coronary heart disease-related hospital care in adult men : Findings from the Helsinki Birth Cohort Study. Annals of Medicine, 49(2), 126-133. https://doi.org/10.1080/07853890.2016.1241426
Published in
Annals of MedicineAuthors
Date
2017Discipline
Gerontologia ja kansanterveysGerontologian tutkimuskeskusHyvinvoinnin tutkimuksen yhteisöGerontology and Public HealthGerontology Research CenterSchool of WellbeingCopyright
© 2016 Informa UK Limited, trading as Taylor & Francis Group. This is a final draft version of an article whose final and definitive form has been published by Taylor & Francis. Published in this repository with the kind permission of the publisher.
Aim: We investigated, among those who had been hospitalized at least once due to coronary heart disease (CHD), the relationship between ponderal index (PI, birthweight/length3) at birth, a measure of thinness, and the age at first hospitalization due to CHD, the number of CHD-related hospital care episodes, and cost of CHD-related hospital care from young adulthood to old age.
Methods and results: Data from the Helsinki Birth Cohort Study included 964 men born in Helsinki, Finland during 1934–1944, who had been hospitalized due to CHD and had birth anthropometrics data. PI (kg/m3) was categorized into low (<25.0), medium (25.0–27.5), and high (>27.5). CHD-related hospital care data were available from 1971 to 2013. We observed an earlier onset of (p = .014 for linearity) and a higher rate of CHD-related hospital care episodes among those in the lowest PI group (incidence rate ratio: 1.35 [95% confidence interval: 1.16–1.59, p < .001]), compared to the highest PI group. CHD-related hospital care costs in the lowest PI group were 25% (p = .001, 4% to 46%) higher compared to those in the highest PI group.
Discussion: Thinness at birth is associated with earlier onset, higher prevalence, and higher accumulated costs of CHD-related hospital in-patient care among men who developed CHD.
...


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Informa Healthcare ; Taylor & Francis Group; Finnish Medical Society DuodecimISSN Search the Publication Forum
0785-3890Publication in research information system
https://converis.jyu.fi/converis/portal/detail/Publication/26230647
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- Liikuntatieteiden tiedekunta [2599]
Related funder(s)
Academy of FinlandFunding program(s)
Academy Research Fellow, AoF
Additional information about funding
HBCS was supported by Emil Aaltonen Foundation, Finnish Foundation for Diabetes Research, Novo Nordisk Foundation, Signe and Ane Gyllenberg Foundation, Samfundet Folkhälsan, Finska Läkaresällskapet, Liv och Hälsa, Finnish Foundation for Cardiovascular Research. The Academy of Finland supported MEvB [grant No. 250681, 294530], MBvB [grant No. 294530], EK [grant No. 127437, 129306, 130326, 134791, and 2639249], and JGE [grant No. 129369, 129907, 135072, 129255, and 126775]. Folkhälsan Research Center has supported MEvB and MBvB. The research leading to these results has received funding from the European Commission within the 7th Framework Programme (DORIAN, grant agreement no 278603) and EU H2020-PHC-2014-DynaHealth grant no. 633595.

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