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• Age but not menopausal status is linked to lower resting energy expenditure 

  Karppinen, Jari E.; Wiklund, Petri; Ihalainen, Johanna K.; Juppi, Hanna-Kaarina; Isola, Ville; Hyvärinen, Matti; Ahokas, Essi K.; Kujala, Urho M.; Laukkanen, Jari; Hulmi, Juha J.; Ahtiainen, Juha P.; Cheng, Sulin; Laakkonen, Eija K. (Oxford University Press; The Endocrine Society, 2023)

  Context It remains uncertain whether aging before late adulthood and menopause are associated with fat-free mass and fat mass–adjusted resting energy expenditure (REEadj). Objectives We investigated whether REEadj ...

• Menopausal transition alters female skeletal muscle transcriptome 

  Juppi, Hanna-Kaarina; Korhonen, Tia-Marje; Sievänen, Tero; Kovanen, Vuokko; Kujala, Urho M.; Aukee, Pauliina; Cronin, Neil; Sipilä, Sarianna; Karvinen, Sira; Laakkonen, Eija K. (Walter de Gruyter GmbH, 2024)

  Objectives Although skeletal muscle is a target of hormonal regulation, the muscle transcriptome, including messenger-RNA (mRNA), long non-coding RNAs (lncRNAs), and microRNAs (miRNAs) has not previously been studied ...

• Associations of menopausal status and eating behaviour with subjective measures of sleep 

  Lankila, Hannamari; Kuutti, Mari A.; Kekäläinen, Tiia; Hietavala, Enni‐Maria; Laakkonen, Eija K. (Wiley-Blackwell, 2024)

  Eating and sleeping behaviour are known to interact with each other, yet research is limited in the context of menopausal women. The aim of this study was to examine whether menopausal status is associated with perceived ...

• Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement 

  Kangas, Reeta; Morsiani, Cristina; Pizza, Grazia; Lanzarini, Catia; Aukee, Pauliina; Kaprio, Jaakko; Sipilä, Sarianna; Franceschi, Claudio; Kovanen, Vuokko; Laakkonen, Eija; Capri, Miriam (Impact Journals, 2018)

  Tissue-specific effects of 17β-estradiol are delivered via both estrogen receptors and microRNAs (miRs). Menopause is known to affect the whole-body fat distribution in women. This investigation aimed at identifying ...

• Design and protocol of Estrogenic Regulation of Muscle Apoptosis (ERMA) study with 47 to 55-year-old women's cohort : novel results show menopause-related differences in blood count 

  Kovanen, Vuokko; Aukee, Pauliina; Kokko, Katja; Finni Juutinen, Taija; Tarkka, Ina; Tammelin, Tuija; Kujala, Urho; Sipilä, Sarianna; Laakkonen, Eija (Lippincott Williams & Wilkins, 2018)

  Objective: The multidisciplinary Estrogenic Regulation of Muscle Apoptosis (ERMA) study was designed to reveal how hormonal differences over the menopausal stages affect the physiological and psychological functioning ...