Biocompatible Hydrogelators Based on Bile Acid Ethyl Amides
Kuosmanen, R., Puttreddy, R., Willman, R.-M., Äijäläinen, I., Galandáková, A., Ulrichová, J., Salo, H., Rissanen, K., & Sievänen, E. (2016). Biocompatible Hydrogelators Based on Bile Acid Ethyl Amides. Steroids, 108, 7-16. https://doi.org/10.1016/j.steroids.2016.02.014
© 2016 Elsevier Inc. This is a final draft version of an article whose final and definitive form has been published by Elsevier. Published in this repository with the kind permission of the publisher.
Four novel bile acid ethyl amides were synthetized using a well-known method. All the four compounds were characterized by IR, SEM, and X-ray crystal analyses. In addition, the cytotoxicity of the compounds was tested. Two of the prepared compounds formed organogels. Lithocholic acid derivative 1 formed hydrogels as 1% and 2% (w/v) in four different aqueous solutions. This is very intriguing regarding possible uses in biomedicine.