Temporal dynamics of Puumala hantavirus infection in cyclic populations of bank voles
Voutilainen, L., Kallio, E., Niemimaa, J., Vapalahti, O., & Henttonen, H. (2016). Temporal dynamics of Puumala hantavirus infection in cyclic populations of bank voles. Scientific Reports, 6, Article 21323. https://doi.org/10.1038/srep21323
Published inScientific Reports
© 2016 the Authors. This is an open access article licensed under a Creative Commons Attribution 4.0 International License.
Understanding the dynamics of zoonotic pathogens in their reservoir host populations is a prerequisite for predicting and preventing human disease epidemics. The human infection risk of Puumala hantavirus (PUUV) is highest in northern Europe, where populations of the rodent host (bank vole, Myodes glareolus) undergo cyclic fluctuations. We conducted a 7-year capture-mark-recapture study to monitor seasonal and multiannual patterns of the PUUV infection rate in bank vole populations exhibiting a 3-year density cycle. Infected bank voles were most abundant in mid-winter months during years of increasing or peak host density. Prevalence of PUUV infection in bank voles exhibited a regular, seasonal pattern reflecting the annual population turnover and accumulation of infections within each year cohort. In autumn, the PUUV transmission rate tracked increasing host abundance, suggesting a density-dependent transmission. However, prevalence of PUUV infection was similar during the increase and peak years of the density cycle despite a twofold difference in host density. This may result from the high proportion of individuals carrying maternal antibodies constraining transmission during the cycle peak years. Our exceptionally intensive and long-term dataset provides a solid basis on which to develop models to predict the dynamic public health threat posed by PUUV in northern Europe. ...
PublisherNature Publishing Group
Dataset related to the publicationhttps://doi.org/10.5061/dryad.g8140
Publication in research information system
MetadataShow full item record
Additional information about fundinghis study was financially supported by Kone Foundation (www.koneensaatio.fi/en), Emil Aaltonen Foundation (www.emilaaltonen.fi/eng.htm), Jenny and Antti Wihuri Foundation (www.wihurinrahasto.fi/foundation.html), Academy of Finland (grant no. 250524 to ERK), the European Commission Project QLK2-CT-2002-01358; GOCE-CT-2003-010284 EDEN (www.eden-fp6project.net), and the EU grant FP7-261504 EDENext (http://www.edenext.eu) and is catalogued by the EDENext Steering Committee as EDENext131. The contents of this publication are the sole responsibility of the authors and do not necessarily reflect the views of the European Commission. ...
Except where otherwise noted, this item's license is described as © 2016 the Authors. This is an open access article licensed under a Creative Commons Attribution 4.0 International License.
Showing items with similar title or keywords.
Rikalainen, Kaisa (University of Jyväskylä, 2013)
Maintenance of genetic diversity in cyclic populations - a longitudinal analysis in Myodes glareolus Rikalainen, Kaisa; Aspi, Jouni; Galarza, Juan; Koskela, Esa; Mappes, Tapio (Wiley-Blackwell, 2012)Conspicuous cyclic changes in population density characterize many populations of small northern rodents. The extreme crashes in individual number are expected to reduce the amount of genetic variation within a population ...
Marjomäki, Timo J.; Auvinen, Heikki; Helminen, Harri; Huusko, Ari; Huuskonen, Hannu; Hyvärinen, Pekka; Jurvelius, Juha; Sarvala, Jouko; Valkeajärvi, Pentti; Viljanen, Markku; Karjalainen, Juha (Finnish Zoological and Botanical Publishing Board, 2021)The tendency towards two-year cyclicity is considered typical of many Fennoscandian vendace populations, especially in fluctuation of recruitment, based on time series of individual lakes. We used two robust ...
Cayol, Claire (University of Jyväskylä, 2017)Infectious diseases are amongst the ten major causes of human mortality worldwide, 60% of them being animal-borne. Variations of abiotic and biotic conditions are likely to modify the transmission of parasites and ...
Ylönen, Hannu (1989)The social organization and behavioural ecology of Clethrionomys voles were studied in Konnevesi, Central Finland in the years 1982 - 88. The study consisted of long-term comparative work on an enclosed population of the ...