Hippocampal theta-band activity and trace eyeblink conditioning in rabbits
Nokia, M., Penttonen, M., Korhonen, T., & Wikgren, J. (2009). Hippocampal theta-band activity and trace eyeblink conditioning in rabbits. Behavioral Neuroscience, 123(3), 631-640. https://doi.org/10.1037/a0015334
Published inBehavioral Neuroscience
DisciplinePsykologiaMonitieteinen aivotutkimuskeskusPsychologyCentre for Interdisciplinary Brain Research
© 2009 American Psychological Association. This is a final draft version of an article whose final and definitive form has been published by APA. Published in this repository with the kind permission of the publisher
The authors examined the relationship between hippocampal theta activity and trace eyeblink conditioning. Hippocampal electrophysiological local field potentials were recorded before, during, and after conditioning or explicitly unpaired training sessions in adult male New Zealand White rabbits. As expected, a high relative power of theta activity (theta ratio) in the hippocampus predicted faster acquisition of the conditioned response during trace conditioning but, contrary to previous results obtained using the delay paradigm, only in the initial stage of learning. The presentation of the conditioned stimulus overall elicited an increase in the hippocampal theta ratio. The theta ratio decreased in the unpaired group as a function of training, remained high throughout conditioning in the fast learners, and rapidly increased in the slow learners initially showing a low theta ratio. Our results indicate a reciprocal connection between the hippocampal oscillatory activity and associative learning. The hippocampal theta ratio seems to reflect changes and differences in the subjects’ alertness and responsiveness to external stimuli, which affect the rate of learning and are, in turn, affected by both conditioning and unpaired training. ...
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Nokia, Miriam; Penttonen, Markku; Korhonen, Tapani; Wikgren, Jan (Elsevier, 2008)In 1978, Berry and Thompson showed that the amount of theta (3–8 Hz) activity in the spontaneous hippocampal EEG predicted learning rate in subsequent eyeblink conditioning in rabbits. More recently, the absence of theta ...
Hippocampal theta activity is selectively associated with contingency detection but not discrimination in rabbit discrimination-reversal eyeblink conditioning Nokia, Miriam; Wikgren, Jan (Wiley, 2010)The relative power of the hippocampal theta-band (∼6 Hz) activity (theta ratio) is thought to reflect a distinct neural state and has been shown to affect learning rate in classical eyeblink conditioning in rabbits. We ...
Nokia, Miriam (University of Jyväskylä, 2009)
Raussi, Pekka (2014)
Hippocampal ripple-contingent training accelerates trace eyeblink conditioning and retards extinction in rabbits Nokia, Miriam; Penttonen, Markku; Wikgren, Jan (Society for Neuroscience, 2010)There are at least two distinct oscillatory states of the hippocampus that are related to distinct behavioral patterns. Theta (4–12 Hz) oscillation has been suggested to indicate selective attention during which the animal ...