Impaired geometric properties of tibia in older women with hip fracture history
Mikkola, T., Sipilä, S., Portegijs, E., Kallinen, M., Alén, M., Kiviranta, I., Pekkonen, M., & Heinonen, A. (2007). Impaired geometric properties of tibia in older women with hip fracture history. Osteoporosis International, 18(8), 1083-1090. https://doi.org/10.1007/s00198-007-0352-x
Julkaistu sarjassa
Osteoporosis InternationalTekijät
Päivämäärä
2007Oppiaine
FysioterapiaGerontologia ja kansanterveysGerontologian tutkimuskeskusHyvinvoinnin tutkimuksen yhteisöPhysiotherapyGerontology and Public HealthGerontology Research CenterSchool of WellbeingTekijänoikeudet
© Springer (2007). This is a final draft version of an article whose final and definitive form has been published by Springer.
Introduction The purpose of this study was to evaluate side-to-side differences in tibial
mineral mass and geometry after hip fracture, and to assess the determinants of such
differences.
Methods Thirty-eight 60- to 85-year-old women with a previous hip fracture and twenty-two
same-aged control women without fractures participated in the study. Bone characteristics of
the distal tibia and tibial shaft of both legs were assessed using pQCT in order to compare the
side-to-side differences of tibias between the two groups.
Results The subjects with fracture history had significantly (p≤0.05, analysis of covariance)
larger side-to-side differences than the controls in tibial shaft BMC (-4.9% vs. -0.5%), cortical
area (-5.2% vs. 0.1%) and polar moment of inertia (Ipolar) (-5.6% vs. -0.8%) and in distal tibia
BMC (-5.1% vs. -1.4%) and Ipolar (-7.5% vs. -2.4%). In the fracture patients, the side-to-side
differences in muscle characteristics explained 23 to 44% of the variances in the side-to-side
differences in bone mass and geometry.
Conclusions Hip fracture results in reduced bone mass and impaired bone geometry in the
tibia of the affected limb in older women. Muscle-induced loading may have a considerable
role in the recovery of bone mineral mass and geometry after hip fracture.
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1433-2965Asiasanat
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https://converis.jyu.fi/converis/portal/detail/Publication/16958538
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