The oocyte derived growth factors, GDF9 and GDF9B, and their biological activities in 'in vitro' cell models
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In vitro glycoengineering of a monoclonal antibody produced in insect cells
Zhurina, Anastasiia (2024)Sugar modifications, in particular, N-glycans, largely determine protein quality, functionality, and, in case of therapeutic biomolecules, safety. Therapeutic monoclonal antibodies (mAbs) generate immune response through ... -
A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses
Saarinen, Niila V. V.; Laiho, Jutta E.; Richardson, Sarah J.; Zeissler, Marie; Stone, Virginia M.; Marjomäki, Varpu; Kantoluoto, Tino; Horwitz, Marc S.; Sioofy-Khojine, Amirbabak; Honkimaa, Anni; Hankaniemi, Minna M.; Flodström-Tullberg, Malin; Hyöty, Heikki; Hytönen, Vesa P.; Laitinen, Olli H. (Nature Publishing Group, 2018)Enteroviruses (EVs) are common RNA viruses that cause diseases ranging from rash to paralytic poliomyelitis. For example, EV-A and EV-C viruses cause hand-foot and mouth disease and EV-B viruses cause encephalitis and ... -
Nanodevices by DNA based gold nanostructures
Tapio, Kosti (University of Jyväskylä, 2017)In this thesis DNA based structures were utilized to create gold nanostructures for nanosensing and nanoelectronic applications. In the past, both of these fields have been dominated by the conventional lithography methods, ... -
Covalent functionalization of graphene oxide with proteins
Korhonen, Elsa (2021)Pro gradu -tutkielman kirjallisuusosassa perehdyttiin menetelmiin, jotka voisivat soveltua proteiinien kiinnittämiseen grafeenioksidin pintaan kovalenttisen sitoutumisen kautta. Kokeellisessa osassa oli tavoitteena kiinnittää ...
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