Modifying the terminal phenyl group of monomethine cyanine dyes as a pathway to brighter nucleic acid probes
Alaranta, J. M., Valkonen, A. M., Shroff, S. S., Marjomäki, V. S., Rissanen, K., & Lahtinen, T. M. (2024). Modifying the terminal phenyl group of monomethine cyanine dyes as a pathway to brighter nucleic acid probes. New Journal of Chemistry, Advance Article. https://doi.org/10.1039/d3nj05400d
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New Journal of ChemistryDate
2024Discipline
Orgaaninen kemiaSolu- ja molekyylibiologiaNanoscience CenterOrganic ChemistryCell and Molecular BiologyNanoscience CenterCopyright
© 2024 The Royal Society of Chemistry and the Centre National de la Recherche Scientifique
Three novel monomethine cyanine dyes were synthesized carrying electron donating groups to obtain
even brighter nucleic acids probes. Photophysical properties of these dyes were evaluated with DNA and
selected dyes with RNA. A great variation in brightness and binding properties of the dyes was observed.
Moreover the X-ray crystal structures are presented for two dyes.
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Royal Society of Chemistry (RSC)ISSN Search the Publication Forum
1144-0546Publication in research information system
https://converis.jyu.fi/converis/portal/detail/Publication/207419951
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Research Council of FinlandFunding program(s)
Academy Project, AoFAdditional information about funding
Kari Rissanen gratefully acknowledge the Academy of Finland (grant number: 351121).License
Except where otherwise noted, this item's license is described as CC BY 3.0