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dc.contributor.authorRigaud, Cyril
dc.contributor.authorHärme, Julia
dc.contributor.authorVehniäinen, Eeva-Riikka
dc.date.accessioned2022-05-03T06:25:10Z
dc.date.available2022-05-03T06:25:10Z
dc.date.issued2022
dc.identifier.citationRigaud, C., Härme, J., & Vehniäinen, E.-R. (2022). Salmo trutta is more sensitive than Oncorhynchus mykiss to early-life stage exposure to retene. <i>Comparative Biochemistry and Physiology C: Toxicology and Pharmacology</i>, <i>252</i>, Article 109219. <a href="https://doi.org/10.1016/j.cbpc.2021.109219" target="_blank">https://doi.org/10.1016/j.cbpc.2021.109219</a>
dc.identifier.otherCONVID_101780722
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/80862
dc.description.abstractSalmonids are known to be among the most sensitive fish to dioxin-like compounds (DLCs), but very little is known about the sensitivity of the brown trout (Salmo trutta), which has declined and is endangered in several countries of Europe and Western Asia. We investigated the sensitivity of brown trout larvae to a widespread dioxin-like PAH, retene (3.2 to 320 μg.L−1), compared to the larvae of a salmonid commonly used in toxicology studies, the rainbow trout (Oncorhynchus mykiss). Mortality, growth, cyp1a induction and the occurrence of deformities were measured after 15 days of exposure. Brown trout larvae showed a significantly higher mortality at 320 μg.L−1 compared to rainbow trout larvae. While the occurrence of deformities was only significantly increased at 320 μg.L−1 for the rainbow trout, brown trout larvae displayed pericardial edemas and hemorrhages already at 10 or 100 μg.L−1. cyp1a induction was increased significantly already at ≥3.2 μg.L−1 for the brown trout, versus ≥32 μg.L−1 for the rainbow trout. Least square regression analysis of the concentration-response relationships suggested that S. trutta larvae were at least 2 times more sensitive than O. mykiss larvae for cyp1a induction. The present study suggests that S. trutta larvae are more sensitive than O. mykiss larvae to a potent DLC, retene. As it is possible that S. trutta populations have declined partly because of pollution by DLCs, we recommend generating more data regarding the sensitivity of threatened fish populations, in order to ensure better risk assessment.en
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofseriesComparative Biochemistry and Physiology C: Toxicology and Pharmacology
dc.rightsCC BY 4.0
dc.subject.otherPAHs
dc.subject.otherRetene
dc.subject.otherSalmonids
dc.subject.otherCYP1A
dc.subject.otherEmbryotoxicity
dc.subject.otherAhR
dc.titleSalmo trutta is more sensitive than Oncorhynchus mykiss to early-life stage exposure to retene
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202205032526
dc.contributor.laitosBio- ja ympäristötieteiden laitosfi
dc.contributor.laitosDepartment of Biological and Environmental Scienceen
dc.contributor.oppiaineYmpäristötiedefi
dc.contributor.oppiaineEnvironmental Scienceen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.description.reviewstatuspeerReviewed
dc.relation.issn1532-0456
dc.relation.volume252
dc.type.versionpublishedVersion
dc.rights.copyright© 2022 The Authors. Published by Elsevier Inc.
dc.rights.accesslevelopenAccessfi
dc.relation.grantnumber319284
dc.relation.grantnumber285296
dc.relation.grantnumber294066
dc.subject.ysoPAH-yhdisteet
dc.subject.ysolohikalat
dc.subject.ysotaimen
dc.subject.ysoepämuodostumat
dc.subject.ysohaitalliset aineet
dc.subject.ysokuolleisuus
dc.subject.ysokirjolohi
dc.subject.ysoekotoksikologia
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p10718
jyx.subject.urihttp://www.yso.fi/onto/yso/p4245
jyx.subject.urihttp://www.yso.fi/onto/yso/p13633
jyx.subject.urihttp://www.yso.fi/onto/yso/p6004
jyx.subject.urihttp://www.yso.fi/onto/yso/p7067
jyx.subject.urihttp://www.yso.fi/onto/yso/p5003
jyx.subject.urihttp://www.yso.fi/onto/yso/p12317
jyx.subject.urihttp://www.yso.fi/onto/yso/p19671
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/
dc.relation.doi10.1016/j.cbpc.2021.109219
dc.relation.funderSuomen Akatemiafi
dc.relation.funderSuomen Akatemiafi
dc.relation.funderSuomen Akatemiafi
dc.relation.funderAcademy of Finlanden
dc.relation.funderAcademy of Finlanden
dc.relation.funderAcademy of Finlanden
jyx.fundingprogramAkatemiatutkijan tutkimuskulut, SAfi
jyx.fundingprogramAkatemiatutkijan tehtävä, SAfi
jyx.fundingprogramAkatemiatutkijan tutkimuskulut, SAfi
jyx.fundingprogramResearch costs of Academy Research Fellow, AoFen
jyx.fundingprogramResearch post as Academy Research Fellow, AoFen
jyx.fundingprogramResearch costs of Academy Research Fellow, AoFen


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