Show simple item record

dc.contributor.authorKuosmanen, Riikka T.
dc.contributor.authorTruong, Khai‐Nghi
dc.contributor.authorRissanen, Kari T.
dc.contributor.authorSievänen, Elina I.
dc.date.accessioned2021-11-29T14:00:42Z
dc.date.available2021-11-29T14:00:42Z
dc.date.issued2021
dc.identifier.citationKuosmanen, R. T., Truong, K., Rissanen, K. T., & Sievänen, E. I. (2021). The Effect of the Side Chain on Gelation Properties of Bile Acid Alkyl Amides. <i>ChemistryOpen</i>, <i>10</i>(11), 1150-1157. <a href="https://doi.org/10.1002/open.202100245" target="_blank">https://doi.org/10.1002/open.202100245</a>
dc.identifier.otherCONVID_102232337
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/78820
dc.description.abstractSix bile acid alkyl amide derivatives were studied with respect to their gelation properties. The derivatives were composed of three different bile acids with hexyl or cyclohexyl side chains. The gelation behaviour of all six compounds were studied for 36 solvents with varying polarities. Gelation was observed mainly in aromatic solvents, which is characteristic for bile-acid-based low molecular weight gelators. Out of 108 bile acid-solvent combinations, a total of 44 gel systems were formed, 28 of which from lithocholic acid derivatives, only two from deoxycholic acid derivatives, and 14 from cholic acid derivatives. The majority of the gel systems were formed from bile acids with hexyl side chains, contrary to the cyclohexyl group, which seems to be a poor gelation moiety. These results indicate that the spatial demand of the side chain is the key feature for the gelation properties of the bile acid amides.en
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherWiley-VCH Verlag
dc.relation.ispartofseriesChemistryOpen
dc.rightsCC BY-NC 4.0
dc.subject.otherbile acid amides
dc.subject.otherintermolecular interactions
dc.subject.othersolvent influence
dc.subject.othersupramolecular gels
dc.subject.otherX-ray crystallography
dc.titleThe Effect of the Side Chain on Gelation Properties of Bile Acid Alkyl Amides
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202111295825
dc.contributor.laitosKemian laitosfi
dc.contributor.laitosDepartment of Chemistryen
dc.contributor.oppiaineOrgaaninen kemiafi
dc.contributor.oppiaineOrganic Chemistryen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.description.reviewstatuspeerReviewed
dc.format.pagerange1150-1157
dc.relation.issn2191-1363
dc.relation.numberinseries11
dc.relation.volume10
dc.type.versionpublishedVersion
dc.rights.copyright© 2021 The Authors. Published by Wiley-VCH GmbH.
dc.rights.accesslevelopenAccessfi
dc.subject.ysosupramolekulaarinen kemia
dc.subject.ysosappihapot
dc.subject.ysogeelit
dc.subject.ysoamidit
dc.subject.ysoröntgenkristallografia
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p37759
jyx.subject.urihttp://www.yso.fi/onto/yso/p25609
jyx.subject.urihttp://www.yso.fi/onto/yso/p12973
jyx.subject.urihttp://www.yso.fi/onto/yso/p20965
jyx.subject.urihttp://www.yso.fi/onto/yso/p29058
dc.rights.urlhttps://creativecommons.org/licenses/by-nc/4.0/
dc.relation.doi10.1002/open.202100245
jyx.fundinginformationUniversity of Jyvaskyla is acknowledged for financial support.


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

CC BY-NC 4.0
Except where otherwise noted, this item's license is described as CC BY-NC 4.0