Toxicological and bioactivity evaluation of blackcurrant press cake, sea buckthorn leaves and bark from Scots pine and Norway spruce extracts under a green integrated approach
Pap, N., Reshamwala, D., Korpinen, R., Kilpeläinen, P., Fidelis, M., Furtado, M. M., Sant’Ana, A. S., Wen, M., Zhang, L., Hellström, J., Marnilla, P., Mattila, P., Sarjala, T., Yang, B., dos Santos Lima, A., Azevedo, L., Marjomäki, V., & Granato, D. (2021). Toxicological and bioactivity evaluation of blackcurrant press cake, sea buckthorn leaves and bark from Scots pine and Norway spruce extracts under a green integrated approach. Food and Chemical Toxicology, 153, Article 112284. https://doi.org/10.1016/j.fct.2021.112284
Published inFood and Chemical Toxicology
© 2021 The Authors. Published by Elsevier Ltd.
Aqueous extracts from blackcurrant press cake (BC), Norway spruce bark (NS), Scots pine bark (SP), and sea buckthorn leaves (SB) were obtained using maceration and pressurized hot water and tested for their bioactivities. Maceration provided the extraction of higher dry matter contents, including total phenolics (TPC), anthocyanins, and condensed tannins, which also impacted higher antioxidant activity. NS and SB extracts presented the highest mean values of TPC and antioxidant activity. Individually, NS extract presented high contents of proanthocyanidins, resveratrol, and some phenolic acids. In contrast, SB contained a high concentration of ellagitannins, ellagic acid, and quercetin, explaining the antioxidant activity and antibacterial effects. SP and BC extracts had the lowest TPC and antioxidant activity. However, BC had strong antiviral efficacy, whereas SP can be considered a potential ingredient to inhibit α-amylase. Except for BC, the other extracts decreased reactive oxygen species (ROS) generation in HCT8 and A549 cells. Extracts did not inhibit the production of TNF-alpha in lipopolysaccharide-stimulated THP-1 macrophages but inhibited the ROS generation during the THP-1 cell respiratory burst. The recovery of antioxidant compounds from these by-products is incentivized for high value-added applications. ...
ISSN Search the Publication Forum0278-6915
Publication in research information system
MetadataShow full item record
Additional information about fundingThe authors thank Luke for providing funds for this project (Power-Xtract – 41007–00185200). Sant’Ana and Furtado thank the support of Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Finance Code 001) and Conselho Nacional de Desenvolvimento Científico e Tecnológico (302763/2014-7, and 305804/2017-0).
Showing items with similar title or keywords.
Enzyme-assisted extraction of anthocyanins and other phenolic compounds from blackcurrant (Ribes nigrum L.) press cake : From processing to bioactivities Granato, Daniel; Fidelis, Marina; Haapakoski, Marjo; dos Santos Lima, Amanda; Viil, Janeli; Hellström, Jarkko; Rätsep, Reelika; Kaldmäe, Hedi; Bleive, Uko; Azevedo, Luciana; Marjomäki, Varpu; Zharkovsky, Alexander; Pap, Nora (Elsevier Ltd., 2022)The effects of commercial enzymes (pectinases, cellulases, beta-1-3-glucanases, and pectin lyases) on the recovery of anthocyanins and polyphenols from blackcurrant press cake were studied considering two solid:solvent ...
Salix spp. Bark Hot Water Extracts Show Antiviral, Antibacterial, and Antioxidant Activities : The Bioactive Properties of 16 Clones Tienaho, Jenni; Reshamwala, Dhanik; Sarjala, Tytti; Kilpeläinen, Petri; Liimatainen, Jaana; Dou, Jinze; Viherä-Aarnio, Anneli; Linnakoski, Riikka; Marjomäki, Varpu; Jyske, Tuula (Frontiers Media SA, 2021)Earlier studies have shown that the bark of Salix L. species (Salicaceae family) is rich in extractives, such as diverse bioactive phenolic compounds. However, we lack knowledge on the bioactive properties of the bark of ...
Effect of Seasonal Storage on Single-Stem Bark Extractives of Norway Spruce (Picea abies) Halmemies, Eelis S.; Brännström, Hanna E.; Nurmi, Juha; Läspä, Otto; Alén, Raimo (MDPI, 2021)Increasing the net value of forestry side-streams has both ecological as well as economic benefits for emerging biorefining industries. Spruce bark represents one of the nature’s abundant sources of valuable extractives. ...
Field-Grown and In Vitro Propagated Round-Leaved Sundew (Drosera rotundifolia L.) Show Differences in Metabolic Profiles and Biological Activities Tienaho, Jenni; Reshamwala, Dhanik; Karonen, Maarit; Silvan, Niko; Korpela, Leila; Marjomäki, Varpu; Sarjala, Tytti (MDPI AG, 2021)Drosera rotundifolia L. is a carnivorous plant used in traditional medicine for its therapeutic properties. Because of its small size, its collection in nature is laborious and different cultivation methods have been studied ...
The effect of thermal drying on the contents of condensed tannins and stilbenes in Norway spruce (Picea abies [L.] Karst.) sawmill bark Jylhä, Paula; Halmemies, Eelis; Hellström, Jarkko; Hujala, Maija; Kilpeläinen, Petri; Brännström, Hanna (Elsevier BV, 2021)Norway spruce (Picea abies (L.) Karst.) bark contains marked amounts of polyphenolic compounds. Condensed tannins (CTs) and stilbenes show commercial potential as antioxidants, antimicrobials, preservatives in food and ...