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dc.contributor.authorLopez, Pedro
dc.contributor.authorRadaelli, Regis
dc.contributor.authorTaaffe, Dennis R.
dc.contributor.authorNewton, Robert U.
dc.contributor.authorGalvão, Daniel A.
dc.contributor.authorTrajano, Gabriel S.
dc.contributor.authorTeodoro, Juliana
dc.contributor.authorKraemer, William J.
dc.contributor.authorHäkkinen, Keijo
dc.contributor.authorPinto, Ronei S.
dc.date.accessioned2021-05-25T09:58:31Z
dc.date.available2021-05-25T09:58:31Z
dc.date.issued2021
dc.identifier.citationLopez, P., Radaelli, R., Taaffe, D. R., Newton, R. U., Galvão, D. A., Trajano, G. S., Teodoro, J., Kraemer, W. J., Häkkinen, K., & Pinto, R. S. (2021). Resistance Training Load Effects on Muscle Hypertrophy and Strength Gain : Systematic Review and Network Meta-analysis. <i>Medicine and Science in Sports and Exercise</i>, <i>53</i>(6), 1206-1216. <a href="https://doi.org/10.1249/MSS.0000000000002585" target="_blank">https://doi.org/10.1249/MSS.0000000000002585</a>
dc.identifier.otherCONVID_51472487
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/75929
dc.description.abstractPurpose: To analyse the effect of resistance training (RT) performed until volitional failure with low-, moderate- and high-loads on muscle hypertrophy and muscle strength in healthy adults; and assess the possible participant-, design-, and training-related covariates which may affect the adaptations. Methods: Using PRISMA guidelines, MEDLINE, CINAHL, EMBASE, SPORTDiscus, and Web of Science databases were searched. Including only studies that performed sets to volitional failure, the effects of low- (>15 RM), moderate- (9-15 RM), and high-load (≤8 RM) RT were examined in healthy adults. Network meta-analysis was undertaken to calculate the standardised mean difference (SMD) between RT loads in overall and subgroup analysis involving studies deemed high-quality. Associations between participant-, design-, and training-related covariates with SMD's were assessed by univariate and multivariate network meta-regression analysis. Results: Twenty-eight studies involving 747 healthy adults were included. Although no differences in muscle hypertrophy between RT loads were found in overall (P= .113 - .469) or subgroup analysis (P= .871 - .995), greater effects were observed in untrained participants (P= .033), and participants with some training background who undertook more RT sessions (P= .031 - .045). Muscle strength improvement was superior for both high-load and moderate-load compared to low-load RT in overall and subgroup analysis (SMD= 0.60 - 0.63 and 0.34 - 0.35, respectively; P< .001 - .003), with a non-significant but superior effect for high- compared to moderate-load (SMD= 0.26 - 0.28, P= .068). Conclusion: While muscle hypertrophy improvements appear to be load independent, increases in muscle strength are superior in high-load RT programs. Untrained participants exhibit greater muscle hypertrophy while undertaking more RT sessions provides superior gains in those with previous training experience.en
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofseriesMedicine and Science in Sports and Exercise
dc.rightsCC BY-NC-ND 4.0
dc.titleResistance Training Load Effects on Muscle Hypertrophy and Strength Gain : Systematic Review and Network Meta-analysis
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202105253188
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.contributor.oppiaineValmennus- ja testausoppifi
dc.contributor.oppiaineScience of Sport Coaching and Fitness Testingen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.description.reviewstatuspeerReviewed
dc.format.pagerange1206-1216
dc.relation.issn0195-9131
dc.relation.numberinseries6
dc.relation.volume53
dc.type.versionpublishedVersion
dc.rights.copyright© 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American College of Sports Medicine. T
dc.rights.accesslevelopenAccessfi
dc.subject.ysoharjoitusvaste
dc.subject.ysovoimaharjoittelu
dc.subject.ysolihasmassa
dc.subject.ysometa-analyysi
dc.subject.ysosystemaattiset kirjallisuuskatsaukset
dc.subject.ysolihasvoima
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p24755
jyx.subject.urihttp://www.yso.fi/onto/yso/p16233
jyx.subject.urihttp://www.yso.fi/onto/yso/p29135
jyx.subject.urihttp://www.yso.fi/onto/yso/p27697
jyx.subject.urihttp://www.yso.fi/onto/yso/p29683
jyx.subject.urihttp://www.yso.fi/onto/yso/p23362
dc.rights.urlhttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.relation.doi10.1249/MSS.0000000000002585


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