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dc.contributor.authorSarhan, Ahmed A.M.
dc.contributor.authorHaukka, Matti
dc.contributor.authorBarakat, Assem
dc.contributor.authorBoraei, Ahmed T.A.
dc.date.accessioned2020-12-07T08:51:05Z
dc.date.available2020-12-07T08:51:05Z
dc.date.issued2020
dc.identifier.citationSarhan, A. A., Haukka, M., Barakat, A., & Boraei, A. T. (2020). A novel synthetic approach to pyran-2,4-dione scaffold production : microwave-assisted dimerization, cyclization, and expeditious regioselective conversion into β-enamino-pyran-2,4-diones. <i>Tetrahedron Letters</i>, <i>61</i>(52), Article 152660. <a href="https://doi.org/10.1016/j.tetlet.2020.152660" target="_blank">https://doi.org/10.1016/j.tetlet.2020.152660</a>
dc.identifier.otherCONVID_47047863
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/72986
dc.description.abstractHere, we report a novel, green, simple, low-cost, and rapid methodology for the high-yield production of pyran-2,4-dione scaffolds under microwave irradiation. Regio- and stereoselective conversions of β-diketone systems into β-enaminones were achieved using 18 primary amines and four amino acid esters. Microwave-assisted further cyclization of 3-(β-substitutedvinyl)-6-phenyl-pyran-2,4-dione into 3-benzoyl-4,7-diphenyl-2H,5H-pyrano[4,3-b]pyran-2,5-dione via reaction with ethyl benzoyl acetate.en
dc.format.mimetypeapplication/pdf
dc.languageeng
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofseriesTetrahedron Letters
dc.rightsCC BY-NC-ND 4.0
dc.subject.otherpyran-2,4-dione
dc.subject.othermicrowave
dc.subject.otherβ-enaminones
dc.subject.otherintramolecular cyclization
dc.titleA novel synthetic approach to pyran-2,4-dione scaffold production : microwave-assisted dimerization, cyclization, and expeditious regioselective conversion into β-enamino-pyran-2,4-diones
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202012076936
dc.contributor.laitosKemian laitosfi
dc.contributor.laitosDepartment of Chemistryen
dc.contributor.oppiaineEpäorgaaninen kemiafi
dc.contributor.oppiaineEpäorgaaninen ja analyyttinen kemiafi
dc.contributor.oppiaineInorganic Chemistryen
dc.contributor.oppiaineInorganic and Analytical Chemistryen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.description.reviewstatuspeerReviewed
dc.relation.issn0040-4039
dc.relation.numberinseries52
dc.relation.volume61
dc.type.versionacceptedVersion
dc.rights.copyright© 2020 Elsevier
dc.rights.accesslevelopenAccessfi
dc.subject.ysokemiallinen synteesi
dc.subject.ysomikroaallot
dc.subject.ysoorgaaniset yhdisteet
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p8468
jyx.subject.urihttp://www.yso.fi/onto/yso/p5741
jyx.subject.urihttp://www.yso.fi/onto/yso/p3841
dc.rights.urlhttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.relation.doi10.1016/j.tetlet.2020.152660
jyx.fundinginformationThe authors would like to extend their sincere appreciation to the Researchers Supporting Project Number (RSP-2020/64), King Saud University, Riyadh, Saudi Arabia.


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CC BY-NC-ND 4.0
Except where otherwise noted, this item's license is described as CC BY-NC-ND 4.0