A novel synthetic approach to pyran-2,4-dione scaffold production : microwave-assisted dimerization, cyclization, and expeditious regioselective conversion into β-enamino-pyran-2,4-diones
| dc.contributor.author | Sarhan, Ahmed A.M. | |
| dc.contributor.author | Haukka, Matti | |
| dc.contributor.author | Barakat, Assem | |
| dc.contributor.author | Boraei, Ahmed T.A. | |
| dc.date.accessioned | 2020-12-07T08:51:05Z | |
| dc.date.available | 2020-12-07T08:51:05Z | |
| dc.date.issued | 2020 | |
| dc.identifier.citation | Sarhan, A. A., Haukka, M., Barakat, A., & Boraei, A. T. (2020). A novel synthetic approach to pyran-2,4-dione scaffold production : microwave-assisted dimerization, cyclization, and expeditious regioselective conversion into β-enamino-pyran-2,4-diones. <i>Tetrahedron Letters</i>, <i>61</i>(52), Article 152660. <a href="https://doi.org/10.1016/j.tetlet.2020.152660" target="_blank">https://doi.org/10.1016/j.tetlet.2020.152660</a> | |
| dc.identifier.other | CONVID_47047863 | |
| dc.identifier.uri | https://jyx.jyu.fi/handle/123456789/72986 | |
| dc.description.abstract | Here, we report a novel, green, simple, low-cost, and rapid methodology for the high-yield production of pyran-2,4-dione scaffolds under microwave irradiation. Regio- and stereoselective conversions of β-diketone systems into β-enaminones were achieved using 18 primary amines and four amino acid esters. Microwave-assisted further cyclization of 3-(β-substitutedvinyl)-6-phenyl-pyran-2,4-dione into 3-benzoyl-4,7-diphenyl-2H,5H-pyrano[4,3-b]pyran-2,5-dione via reaction with ethyl benzoyl acetate. | en |
| dc.format.mimetype | application/pdf | |
| dc.language | eng | |
| dc.language.iso | eng | |
| dc.publisher | Elsevier | |
| dc.relation.ispartofseries | Tetrahedron Letters | |
| dc.rights | CC BY-NC-ND 4.0 | |
| dc.subject.other | pyran-2,4-dione | |
| dc.subject.other | microwave | |
| dc.subject.other | β-enaminones | |
| dc.subject.other | intramolecular cyclization | |
| dc.title | A novel synthetic approach to pyran-2,4-dione scaffold production : microwave-assisted dimerization, cyclization, and expeditious regioselective conversion into β-enamino-pyran-2,4-diones | |
| dc.type | research article | |
| dc.identifier.urn | URN:NBN:fi:jyu-202012076936 | |
| dc.contributor.laitos | Kemian laitos | fi |
| dc.contributor.laitos | Department of Chemistry | en |
| dc.contributor.oppiaine | Epäorgaaninen kemia | fi |
| dc.contributor.oppiaine | Epäorgaaninen ja analyyttinen kemia | fi |
| dc.contributor.oppiaine | Inorganic Chemistry | en |
| dc.contributor.oppiaine | Inorganic and Analytical Chemistry | en |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | |
| dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | |
| dc.description.reviewstatus | peerReviewed | |
| dc.relation.issn | 0040-4039 | |
| dc.relation.numberinseries | 52 | |
| dc.relation.volume | 61 | |
| dc.type.version | acceptedVersion | |
| dc.rights.copyright | © 2020 Elsevier | |
| dc.rights.accesslevel | openAccess | fi |
| dc.type.publication | article | |
| dc.subject.yso | kemiallinen synteesi | |
| dc.subject.yso | mikroaallot | |
| dc.subject.yso | orgaaniset yhdisteet | |
| dc.format.content | fulltext | |
| jyx.subject.uri | http://www.yso.fi/onto/yso/p8468 | |
| jyx.subject.uri | http://www.yso.fi/onto/yso/p5741 | |
| jyx.subject.uri | http://www.yso.fi/onto/yso/p3841 | |
| dc.rights.url | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.relation.doi | 10.1016/j.tetlet.2020.152660 | |
| jyx.fundinginformation | The authors would like to extend their sincere appreciation to the Researchers Supporting Project Number (RSP-2020/64), King Saud University, Riyadh, Saudi Arabia. | |
| dc.type.okm | A1 |
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