Effects of military training on plasma amino acid concentrations and their associations with overreaching
Ikonen, J. N., Joro, R., Uusitalo, A. L., Kyröläinen, H., Kovanen, V., Atalay, M., & Tanskanen-Tervo, M. M. (2020). Effects of military training on plasma amino acid concentrations and their associations with overreaching. Experimental Biology and Medicine, 245(12), 1029-1038. https://doi.org/10.1177/1535370220923130
Published inExperimental Biology and Medicine
DisciplineValmennus- ja testausoppiLiikuntafysiologiaGerontologia ja kansanterveysScience of Sport Coaching and Fitness TestingExercise PhysiologyGerontology and Public Health
© Authors, 2020
Amino acids are thought to have a key role in the processes contributing to overreaching development through their metabolic properties and neuronal functions. In the present study, the effects of 10-week military training on the concentrations of 19 amino acids were investigated. Plasma amino acid concentrations were measured at rest from 53 healthy male conscripts on weeks 1, 4, 7, and 9 of their military service. Conscripts were classified as overreached and non-overreached. Overreaching classification was based on fulfilling at least three of five criteria: greater than 5% decrease in maximal oxygen uptake, increased rating perceived exertion (RPE), and decreased lactate-RPE ratio in submaximal marching test, admitting feeling overloaded and both increased scores in fatigue and decreased scores in vigor in the Profile of Mood States Adolescents. Eight conscripts (15%) were classified as overreached; their glutamine–glutamate ratio and alanine and arginine levels were significantly lower (P < 0.05) and glutamate concentration significantly higher (P < 0.05) in comparison to their non-overreached counterparts. The levels of arginine increased (P < 0.05) and tryptophan (P < 0.001) decreased in both groups throughout the study. The tyrosine concentration increased in non-overreached but, in contrast, remained at the same level in overreached individuals (P < 0.05). The results suggest that alterations in the levels of three metabolically important amino acids, alanine, glutamate and arginine, and the possibly neuroactive tyrosine and tryptophan might explain some of the physical and psychological symptoms of overreaching. The present study also confirms the potential use of glutamine–glutamate ratio as a tool for detecting overreaching. ...
Publication in research information system
MetadataShow full item record
- Liikuntatieteiden tiedekunta 
Showing items with similar title or keywords.
Effects of 10 weeks of military training on neuromuscular function in non-overreached and overreached conscripts Piirainen, Jarmo; Rautio, T.; Tanskanen-Tervo, M.M.; Kyröläinen, Heikki; Huovinen, J.; Linnamo, Vesa (Elsevier Ltd, 2019)The purpose of the study was to examine how military training influences neuromuscular function in non-overreached and overreached conscripts. A total of 24 male conscripts participated in the study (8 weeks basic ...
Tanskanen, Minna; Uusitalo, Arja; Kinnunen, Hannu; Häkkinen, Keijo; Kyröläinen, Heikki; Atalay, Mustafa (Wolters Klower Health, 2011)We hypothesized that increased oxidative stress and disrupted redox balance may be predisposing factors and markers for overreaching (OR). Purpose: To examine whether oxidative stress markers and antioxidant status and ...
Serum sex-hormone binding globulin and cortisol concentrations are associated with overreaching during strenuous military training Tanskanen, Minna; Kyröläinen, Heikki; Uusitalo, Arja; Huovinen, Jukka; Nissilä, Juuso; Kinnunen, Hannu; Atalay, Mustafa; Häkkinen, Keijo (Wolters Klowers Health, 2011)The purpose was (a) to study the effect of an 8-week Finnish military basic training period (BT) on physical fitness, body composition, mood state, and serum biochemical parameters among new conscripts; (b) to determine ...
Myrberg, Marianne (2017)Tutkimuksen tarkoituksena oli selvittää hypertrofisen voimaharjoittelun myötä kasvaneen lihaksen koon ja voimatason mahdollisia vaikutuksia veren aminohappopitoisuuksiin meta-bolomiikalla tutkittuna. Tulokset kerättiin ...
Interactive effects of aging and aerobic capacity on energy metabolism–related metabolites of serum, skeletal muscle, and white adipose tissue Zhuang, Haihui; Karvinen, Sira; Törmäkangas, Timo; Zhang, Xiaobo; Ojanen, Xiaowei; Velagapudi, Vidya; Alen, Markku; Britton, Steven L.; Koch, Lauren G.; Kainulainen, Heikki; Cheng, Sulin; Wiklund, Petri (Springer, 2021)Aerobic capacity is a strong predictor of longevity. With aging, aerobic capacity decreases concomitantly with changes in whole body metabolism leading to increased disease risk. To address the role of aerobic capacity, ...