Should inflammatory pathways be targeted for the prevention and treatment of hypertension?
Kunutsor, S. K., & Laukkanen, J. (2019). Should inflammatory pathways be targeted for the prevention and treatment of hypertension?. Heart, 105 (9), 665-667. doi:10.1136/heartjnl-2018-314625
© Author(s) (or their employer(s)) 2019.
Hypertension is the most common modifiable risk factor for cardiovascular disease (CVD)1 and is a leading cause of death globally.2 Hypertension and CVD share common antecedent risk factors which include physical inactivity, obesity and excess alcohol intake.3 Though these established risk factors explain a large proportion of hypertension risk, its pathogenesis is still not fully established as it appears that other additional lifestyle and genetic factors may be involved. There is therefore a need to identify and evaluate putative risk factors that may increase our knowledge of hypertension development, may have causal or predictive relevance, and which will help develop preventive and management strategies.
MetadataShow full item record
- Liikuntatieteiden tiedekunta 
Showing items with similar title or keywords.
Standalone sauna vs exercise followed by sauna on cardiovascular function in non‐naïve sauna users : A comparison of acute effects Lee, Earric; Kostensalo, Joel; Willeit, Peter; Kunutsor, Setor K.; Laukkanen, Tanjaniina; Zaccardi, Francesco; Khan, Hassan; Laukkanen, Jari A. (John Wiley & Sons, 2021)Background and aims Sauna bathing and aerobic exercise have each been shown to affect cardiovascular function. However, direct comparisons between standalone sauna bathing and a combination of exercise and sauna on vascular ...
Overweight and obesity are associated with cardiac adverse structure remodeling in Chinese elderly with hypertension Liu, Cheng; Li, Gang; Laukkanen, Jari A.; Hao, Lan; Zhao, Qianping; Zhang, Jing; Zhang, Xu (Nature Publishing Group, 2019)There is limited information on the association of overweight and obesity with cardiac remodeling in elderly population. Therefore, we investigated whether overweight and obesity are associated with cardiac geometric ...
Kaprio, Jaakko; Bollepalli, Sailalitha; Buchwald, Jadwiga; Iso-Markku, Paula; Korhonen, Tellervo; Kovanen, Vuokko; Kujala, Urho; Laakkonen, Eija K.; Latvala, Antti; Leskinen, Tuija; Lindgren, Noora; Ollikainen, Miina; Piirtola, Maarit; Rantanen, Taina; Rinne, Juha; Rose, Richard J.; Sillanpää, Elina; Silventoinen, Karri; Sipilä, Sarianna; Viljanen, Anne; Vuoksimaa, Eero; Waller, Katja (Cambridge University Press, 2019)The older Finnish Twin Cohort (FTC) was established in 1974. The baseline survey was in 1975, with two follow-up health surveys in 1981 and 1990. The fourth wave of assessments was done in three parts, with a questionnaire ...
Relationship between inflammatory biomarkers and testosterone levels in male master athletes and non-athletes Pinheiro Barbosa, Luca; da Silva Aguiar, Samuel; Anderson Santos, Patrick; Rosa dos Santos, Thiago; Alves Maciel, Larissa; Alves de Deus, Lysleine; Vanerson Passos Neves, Rodrigo; Lopes de Araújo Leite, Patrício; Duarte Gutierrez, Sara; Victor Sousa, Caio; Korhonen, Marko T.; Degens, Hans; Gustavo Simões, Herbert (Elsevier, 2021)Background Aging is often associated with low-grade systemic inflammation and reduced anabolic hormone levels. To investigate whether lifelong exercise training can decrease the age-related low-grade inflammation and ...
Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis Mäki-Nevala, Satu; Ukwattage, Sanjeevi; Wirta, Erkki-Ville; Ahtiainen, Maarit; Ristimäki, Ari; Seppälä, Toni T.; Lepistö, Anna; Mecklin, Jukka-Pekka; Peltomäki, Päivi (MDPI AG, 2021)Immunological and epigenetic changes are interconnected and contribute to tumorigenesis. We determined the immunoprofiles and promoter methylation of inflammation-related genes for colitis-associated colorectal carcinomas ...