Inter and intraspecific genomic divergence in Drosophila montana shows evidence for cold adaptation
Parker, D., Wiberg, R. A. W., Trivedi, U., Tyukmaeva, V., Gharbi, K., Butlin, R. K., Hoikkala, A., Kankare, M., & Ritchie, M. G. (2018). Inter and intraspecific genomic divergence in Drosophila montana shows evidence for cold adaptation. Genome Biology and Evolution, 10(8), 2086-2101. https://doi.org/10.1093/gbe/evy147
Published inGenome Biology and Evolution
© 2018 the Author(s)
The genomes of species that are ecological specialists will likely contain signatures of genomic adaptation to their niche. However, distinguishing genes related to ecological specialism from other sources of selection and more random changes is a challenge. Here, we describe the genome of Drosophila montana, which is the most extremely cold-adapted Drosophila species known. We use branch tests to identify genes showing accelerated divergence in contrasts between cold- and warm-adapted species and identify about 250 genes that show differences, possibly driven by a lower synonymous substitution rate in cold-adapted species. We also look for evidence of accelerated divergence between D. montana and D. virilis, a previously sequenced relative, but do not find strong evidence for divergent selection on coding sequence variation. Divergent genes are involved in a variety of functions, including cuticular and olfactory processes. Finally, we also resequenced three populations of D. montana from across its ecological and geographic range. Outlier loci were more likely to be found on the X chromosome and there was a greater than expected overlap between population outliers and those genes implicated in cold adaptation between Drosophila species, implying some continuity of selective process at these different evolutionary scales. ...
PublisherOxford University Press
Dataset(s) related to the publicationhttps://doi.org/10.5061/dryad.s813p55
Publication in research information system
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Related funder(s)Academy of Finland
Funding program(s)Research post as Academy Research Fellow, AoF; Academy Project, AoF
Additional information about fundingWe would like to thank Paris Veltsos for help with DNA extractions, and RAPiD Genomics (FL, USA) for help with probe design, library preparation, sequencing, and initial analysis of the SNP data for the linkage map. This work was supported by the Academy of Finland to A.H. (projects 132619 and 267244) and to M.K. (projects 268214 and 272927) and Natural Environment Research Council (UK) funding to M.G.R. (Grants NE/E015255/1 and NE/J020818/1) and PhD studentship to D.J.P. (NE/I528634/1). ...
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