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dc.contributor.authorSivula, Leena
dc.contributor.authorVehniäinen, Eeva-Riikka
dc.contributor.authorKarjalainen, Anna
dc.contributor.authorKukkonen, Jussi
dc.date.accessioned2018-07-17T11:17:21Z
dc.date.available2020-12-01T22:35:10Z
dc.date.issued2018
dc.identifier.citationSivula, L., Vehniäinen, E.-R., Karjalainen, A., & Kukkonen, J. (2018). Toxicity of biomining effluents to Daphnia magna : Acute toxicity and transcriptomic biomarkers. <i>Chemosphere</i>, <i>210</i>, 304-311. <a href="https://doi.org/10.1016/j.chemosphere.2018.07.030" target="_blank">https://doi.org/10.1016/j.chemosphere.2018.07.030</a>
dc.identifier.otherCONVID_28156893
dc.identifier.otherTUTKAID_78223
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/58955
dc.description.abstractIncreasing metal consumption is driving the introduction of new techniques such as biomining to exploit low grade ores. The biomining impacts notably aquatic ecosystems, yet, the applicability of ecotoxicological tests to study the complex mixture effects of mining waters is insufficiently understood. The aim of the present work was to test if transcriptomic biomarkers are suitable and sensitive for the ecotoxicity assessment of biomining affected waters. The study site had been affected by a multimetal biomine, and the studied water samples formed a concentration gradient of contamination downstream from the biomining site. Cadmium and nickel were used as positive controls in the toxicity tests. Selected transcriptomic biomarkers, previously shown to be differentially regulated by metals, were used to evaluate the ecotoxicity of the water samples. Parallel samples were used to compare the transcriptomic biomarkers with the conventional acute D. magna toxicity test. In the acute test, one sample was acutely toxic to D. magna, when pH was adjusted according to the standard, whereas, in the native pH, three samples caused total immobility. Monooxygenase was up-regulated by the highest concentration of Cd in control samples and three of the water samples. Vtg-SOD was up-regulated by one of the water samples, and catalase by the second highest concentration of Cd. The results show that transcriptomic biomarkers in D. magna can be used as sensitive bioindicators for metal mixture toxicity assessment in complex environmental water samples.fi
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherPergamon Press
dc.relation.ispartofseriesChemosphere
dc.rightsCC BY-NC-ND 4.0
dc.subject.othermixture toxicity
dc.subject.othermining effluent
dc.subject.othersub-lethal
dc.subject.othermRNA
dc.titleToxicity of biomining effluents to Daphnia magna : Acute toxicity and transcriptomic biomarkers
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201807113517
dc.contributor.laitosBio- ja ympäristötieteiden laitosfi
dc.contributor.laitosDepartment of Biological and Environmental Scienceen
dc.contributor.oppiaineYmpäristötiedefi
dc.contributor.oppiaineEnvironmental Scienceen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2018-07-11T09:15:06Z
dc.description.reviewstatuspeerReviewed
dc.format.pagerange304-311
dc.relation.issn0045-6535
dc.relation.numberinseries0
dc.relation.volume210
dc.type.versionacceptedVersion
dc.rights.copyright© 2018 Elsevier Ltd. All rights reserved.
dc.rights.accesslevelopenAccessfi
dc.relation.grantnumber281800
dc.relation.grantnumber285296
dc.subject.ysovesikirput
dc.subject.ysotranskriptio (biologia)
dc.subject.ysovesien saastuminen
dc.subject.ysokaivosvesi
dc.subject.ysometallit
dc.subject.ysokaivokset
dc.subject.ysobioliuotus
dc.subject.ysomarkkerit
dc.subject.ysolähetti-RNA
dc.subject.ysomyrkyllisyys
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p14681
jyx.subject.urihttp://www.yso.fi/onto/yso/p2788
jyx.subject.urihttp://www.yso.fi/onto/yso/p7659
jyx.subject.urihttp://www.yso.fi/onto/yso/p37776
jyx.subject.urihttp://www.yso.fi/onto/yso/p3097
jyx.subject.urihttp://www.yso.fi/onto/yso/p18684
jyx.subject.urihttp://www.yso.fi/onto/yso/p29415
jyx.subject.urihttp://www.yso.fi/onto/yso/p12288
jyx.subject.urihttp://www.yso.fi/onto/yso/p29072
jyx.subject.urihttp://www.yso.fi/onto/yso/p12637
dc.rights.urlhttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.relation.doi10.1016/j.chemosphere.2018.07.030
dc.relation.funderSuomen Akatemiafi
dc.relation.funderSuomen Akatemiafi
dc.relation.funderAcademy of Finlanden
dc.relation.funderAcademy of Finlanden
jyx.fundingprogramAkatemiahanke, SAfi
jyx.fundingprogramAkatemiatutkijan tehtävä, SAfi
jyx.fundingprogramAcademy Project, AoFen
jyx.fundingprogramResearch post as Academy Research Fellow, AoFen
jyx.fundinginformationWe thank Aurore Merlet for help in the laboratory, Hanna Arola for providing Fig. 1, and Kainuu Centre for economic development, transport and the environment and the former Talvivaara Mining Company, currently Terrafame, for prompt cooperation. The study was supported by Maj and Tor Nessling foundation and The Academy of Finland (281800, 285296).


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