dc.contributor.author | Hirvasniemi, Jukka | |
dc.contributor.author | Thevenot, Jérôme | |
dc.contributor.author | Multanen, Juhani | |
dc.contributor.author | Haapea, Marianne | |
dc.contributor.author | Heinonen, Ari | |
dc.contributor.author | Nieminen, Miika T. | |
dc.contributor.author | Saarakkala, Simo | |
dc.date.accessioned | 2017-11-16T10:08:07Z | |
dc.date.available | 2017-11-16T10:08:07Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Hirvasniemi, J., Thevenot, J., Multanen, J., Haapea, M., Heinonen, A., Nieminen, M. T., & Saarakkala, S. (2017). Association between radiography-based subchondral bone structure and MRI-based cartilage composition in postmenopausal women with mild osteoarthritis. <i>Osteoarthritis and Cartilage</i>, <i>25</i>(12), 2039-2046. <a href="https://doi.org/10.1016/j.joca.2017.09.008" target="_blank">https://doi.org/10.1016/j.joca.2017.09.008</a> | |
dc.identifier.other | CONVID_27258304 | |
dc.identifier.other | TUTKAID_75190 | |
dc.identifier.uri | https://jyx.jyu.fi/handle/123456789/55894 | |
dc.description.abstract | Objective: Our aim was to investigate the relation between radiograph-based subchondral bone structure
and cartilage composition assessed with delayed gadolinium enhanced magnetic resonance imaging of
cartilage (dGEMRIC) and T2 relaxation time.
Design: Ninety-three postmenopausal women (KellgreneLawrence grade 0: n ¼ 13, 1: n ¼ 26, 2: n ¼ 54)
were included. Radiograph-based bone structure was assessed using entropy of the Laplacian-based
image (ELap) and local binary patterns (ELBP), homogeneity indices of the local angles (HIAngles,mean,
HIAngles,Perp, HIAngles,Paral), and horizontal (FDHor) and vertical fractal dimensions (FDVer). Mean dGEMRIC
index and T2 relaxation time of tibial cartilage were calculated to estimate cartilage composition.
Results: HIAngles,mean (rs ¼ 0.22) and HIAngles,Paral (rs ¼ 0.24) in medial subchondral bone were related
(P < 0.05) to dGEMRIC index of the medial tibial cartilage. ELap (rs ¼ 0.23), FDHor,0.34 mm (r ¼ 0.21) and
FDVer,0.68 mm (r ¼ 0.24) in medial subchondral bone were related (P < 0.05) to T2 relaxation time values of
the medial tibial cartilage. FDHor at different scales in lateral subchondral bone were related (P < 0.01) to
dGEMRIC index (r ¼ 0.29e0.41) and T2 values of lateral tibial cartilage (r ¼ 0.28 to 0.36). FDVer at
larger scales were related (P < 0.05) to dGEMRIC index (r ¼ 0.24e0.25) and T2 values of lateral tibial
cartilage (r ¼ 0.21). HIAngles,Paral (r ¼ 0.25) and FDVer,0.68 mm (rs ¼ 0.22) in the lateral tibial trabecular
bone were related (P < 0.05) to dGEMRIC index of the lateral tibial cartilage.
Conclusion: Our results support the presumption that several tissues are affected in the early osteoarthritis
(OA). Furthermore, they indicate that the detailed analysis of radiographs may serve as a complementary
imaging tool for OA studies. | |
dc.language.iso | eng | |
dc.publisher | Elsevier Ltd; OsteoArthritis Research Society International | |
dc.relation.ispartofseries | Osteoarthritis and Cartilage | |
dc.subject.other | röntgentutkimus | |
dc.subject.other | magneettitutkimus | |
dc.subject.other | radiography | |
dc.subject.other | MRI | |
dc.subject.other | osteoarthritis | |
dc.subject.other | bone structure | |
dc.subject.other | cartilage composition | |
dc.title | Association between radiography-based subchondral bone structure and MRI-based cartilage composition in postmenopausal women with mild osteoarthritis | |
dc.type | article | |
dc.identifier.urn | URN:NBN:fi:jyu-201711134225 | |
dc.contributor.laitos | Liikuntatieteellinen tiedekunta | fi |
dc.contributor.laitos | Faculty of Sport and Health Sciences | en |
dc.contributor.oppiaine | Fysioterapia | fi |
dc.contributor.oppiaine | Physiotherapy | en |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | |
dc.date.updated | 2017-11-13T07:15:05Z | |
dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | |
dc.description.reviewstatus | peerReviewed | |
dc.format.pagerange | 2039-2046 | |
dc.relation.issn | 1063-4584 | |
dc.relation.numberinseries | 12 | |
dc.relation.volume | 25 | |
dc.type.version | publishedVersion | |
dc.rights.copyright | © 2017 The Author(s). Published by Elsevier Ltd on behalf of Osteoarthritis Research Society
International. This is an open access article under the CC BY-NC-ND license. | |
dc.rights.accesslevel | openAccess | fi |
dc.subject.yso | nivelrikko | |
dc.subject.yso | polvet | |
dc.subject.yso | luu | |
dc.subject.yso | rusto | |
dc.subject.yso | röntgenhoitajat | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p12334 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p14204 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p24244 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p21729 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p18206 | |
dc.rights.url | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.relation.doi | 10.1016/j.joca.2017.09.008 | |
dc.type.okm | A1 | |