Eco-epidemiology of tick- and rodent-borne pathogens in boreal forests
Julkaistu sarjassa
Jyväskylä studies in biological and environmental scienceTekijät
Päivämäärä
2017Oppiaine
Ekologia ja evoluutiobiologiaInfectious diseases are amongst the ten major causes of human mortality
worldwide, 60% of them being animal-borne. Variations of abiotic and biotic
conditions are likely to modify the transmission of parasites and pathogens
within reservoir species, and, as a consequence, alter the zoonotic risk for
human. My thesis aims at elucidating the dynamics and mechanisms of the
maintenance of ticks, tick-borne pathogens (TBPs) and the Puumala hantavirus
(PUUV) in the reservoir host, the bank vole (Myodes glareolus, BV). In Northern
Europe, tick-borne diseases are growing in importance to human because of the
latitudinal expansion of the tick Ixodes ricinus. Field monitoring revealed that I.
ricinus was the only species found in the vegetation in Central Finland. The
abundance of immature I. ricinus in nature was positively associated with the
BV abundance. The highest risk periods for tick bites on humans were May–
June and September. Ixodes ricinus was positively associated with open water
coverage and human density, which might offer suitable moisture conditions
and anthropogenic modifications favouring the species. The infection of BV
with the zoonotic B. burgdorferi s.l. was associated with the abundance of I.
ricinus at the site, indicating that this tick species was required for the
transmission and persistence of this pathogen. An experiment revealed, for the
first time, that B. afzelii can modify the behaviour and the breeding success of its
host, and these effects are both sex- and size-specific and density-dependent.
Space-state modelling of longitudinal field data revealed that PUUV infection
likelihood was the lowest in BV previously infested with vectors in comparison
to Anaplasma phagocytophilum infected BV, or individuals without any previous
infections. Altogether, this study shows how seasonality, co-infecting
pathogens and host population density influence the risk of tick-borne
pathogens and the zoonotic risk in Central Finland.
...


Julkaisija
University of JyväskyläISBN
978-951-39-7206-6ISSN Hae Julkaisufoorumista
1456-9701Asiasanat
Borrelia burgdorferi s.l Myodes glareolus Puumala hantavirus disease ecology eco-epidemiology reservoir tick-borne pathogens puutiaiset punkit taudinaiheuttajat Borrelia-bakteerit Puumala-virus leviäminen isäntäeläimet myyrät metsämyyrä jyrsijät metsäekosysteemit populaatioekologia boreaalinen vyöhyke ekologia epidemiologia hantavirukset zoonoosit
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Samankaltainen aineisto
Näytetään aineistoja, joilla on samankaltainen nimeke tai asiasanat.
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Rodent host population dynamics drive zoonotic Lyme Borreliosis and Orthohantavirus infections in humans in Northern Europe
Aminikhah, Mahdi; Forsman, Jukka T.; Koskela, Esa; Mappes, Tapio; Sane, Jussi; Ollgren, Jukka; Kivelä, Sami M.; Kallio, Eva R. (Nature Publishing Group, 2021)Zoonotic diseases, caused by pathogens transmitted between other vertebrate animals and humans, pose a major risk to human health. Rodents are important reservoir hosts for many zoonotic pathogens, and rodent population ... -
Borrelia afzelii alters reproductive success in a rodent host
Cayol, Claire; Giermek, Anna; Gomez-Chamorro, Andrea; Hytönen, Jukka; Kallio, Eva; Mappes, Tapio; Salo, Jemiina; Voordouw, Maarten Jeroen; Koskela, Esa (The Royal Society Publishing, 2018)The impact of a pathogen on the fitness and behaviour of its natural host depends upon the host–parasite relationship in a given set of environmental conditions. Here, we experimentally investigated the effects of Borrelia ... -
Experimental ecology on the interaction between the Puumala hantavirus and its host, the bank vole
Kallio, Eva R. (University of Jyväskylä, 2006)Eva Kallio tutki väitöskirjatyössään ihmisissä myyräkuumetta aiheuttavan, Hantaviruksiin kuuluvan Puumala-viruksen ja sen isäntälajin metsämyyrän välistä vuorovaikutussuhdetta. Tutkimuksessa selvisi viruksen säilyvän ... -
Sympatric Ixodes-tick species : pattern of distribution and pathogen transmission within wild rodent populations
Cayol, Claire; Jääskeläinen, Anu; Koskela, Esa; Kyröläinen, Sami; Mappes, Tapio; Siukkola, Anja; Kallio, Eva (Nature Publishing Group, 2018)The generalist tick Ixodes ricinus is the most important vector for tick-borne pathogens (TBP), including Borrelia burgdorferi sensu lato, in Europe. However, the involvement of other sympatric Ixodes ticks, such as the ...
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