Systematic study of physicochemical properties of a homologous series of aminobisphosphonates
Alanne, A.-L., Hyvönen, H., Lahtinen, M., Ylisirniö, M., Turhanen, P., Kolehmainen, E., Peräniemi, S., & Vepsäläinen, J. (2012). Systematic study of physicochemical properties of a homologous series of aminobisphosphonates. Molecules, 17(9), 10928-10945. https://doi.org/10.3390/molecules170910928
Julkaistu sarjassa
MoleculesTekijät
Päivämäärä
2012Tekijänoikeudet
© the Authors, 2012. This is an open access article distributed under the Creative Commons Attribution License.
Aminobisphosphonates, e.g., alendronate and neridronate, are a well known class of molecules used as drugs for various bone diseases. Although these molecules have been available for decades, a detailed understanding of their most important physicochemical properties under comparable conditions is lacking. In this study, ten aminobisphosphonates, H2N(CH2)nC(OH)[P(O)(OH)2]2, in which n = 2–5, 7–11 and 15 have been synthesized. Their aqueous solubility as a function of temperature and pH, pKa-values, thermal stability, IR absorptions, and NMR spectral data for bothliquid (1H, 13C, 31P-NMR) and solid state (13C, 15N and 31P-CPMAS NMR) were determined.
Julkaisija
MDPIAGISSN Hae Julkaisufoorumista
1420-3049Asiasanat
Julkaisu tutkimustietojärjestelmässä
https://converis.jyu.fi/converis/portal/detail/Publication/21605873
Metadata
Näytä kaikki kuvailutiedotKokoelmat
Lisenssi
Ellei muuten mainita, aineiston lisenssi on © the Authors, 2012. This is an open access article distributed under the Creative Commons Attribution License.
Samankaltainen aineisto
Näytetään aineistoja, joilla on samankaltainen nimeke tai asiasanat.
-
Alkyl-Substituted Aminobis(phosphonates) : Efficient Precipitating Agents for Rare Earth Elements, Thorium, and Uranium in Aqueous Solutions
Virtanen, Emilia J.; Perämäki, Siiri; Helttunen, Kaisa; Väisänen, Ari; Moilanen, Jani O. (American Chemical Society (ACS), 2021)The efficient and environmentally sustainable separation process for rare earth elements (REE), especially for adjacent lanthanoids, remains a challenge due to the chemical similarity of REEs. Tetravalent actinoids, thorium, ... -
Self-assembly, physico-chemical characterization, biological, virtual screening, and computational approach of novel 2-amino pyridine derivatives
Makhlouf, Jawher; El Bakri, Youness; Saravanan, Kandasamy; Valkonen, Arto; Smirani, Wajda (Elsevier BV, 2023)Two novel compounds, [Zn(SCN)4] (C5H7N2)2 (I) and (C5H7N2)NCS (II), were successfully synthesized and grown at room temperature by slow evaporation. The investigation of compound's properties was occurred using various ... -
Physico-Chemical Properties and Use of Waste Biomass-Derived Activated Carbons
Lahti, Riikka; Bergna, Davide; Romar, Henrik; Tuuttila, Tero; Hu, Tao; Lassi, Ulla (AIDIC, 2017)Activated carbons are widely used in different industrial processes for example as adsorbents or as support materials. Advantageously these carbons can be prepared from residual or waste biomass materials. Different raw ... -
Growth, single crystal investigation and physico-chemical properties of thiocyanate coordination compounds based on 1,4-dimethylpiperazine
Makhlouf, Jawher; Valkonen, Arto; Smirani, Wajda Sta (Informa UK Limited, 2022)Four new hybrid organic-inorganic compounds based on 1,4-cimethylpiperazinium, [C6H16N2M(SCN)4]·2H2O (M = Co(1), Ni(2)), [(C6H16N2)Cd(SCN)4] (3), and [C6H16N2(SCN)2] (4), were prepared by the evaporation crystal growth ... -
Conduction properties of thin films from a water soluble carbon nanotube/hemicellulose complex
Shao, Dongkai; Yotprayoonsak, Peerapong; Saunajoki, Ville; Ahlskog, Markus; Virtanen, Jorma; Kangas, Veijo; Volodin, Alexander; Haesendonck, Chris Van; Burdanova, Maria; Mosley, Connor; Lloyd-Hughes, James (IOP Publishing, 2018)We have examined the conductive properties of carbon nanotube based thin films, which were prepared via dispersion in water by non-covalent functionalization of the nanotubes with xylan, a type of hemicellulose. Measurements ...
Ellei toisin mainittu, julkisesti saatavilla olevia JYX-metatietoja (poislukien tiivistelmät) saa vapaasti uudelleenkäyttää CC0-lisenssillä.