Caffeine as a Gelator
Nonappa & Kolehmainen, E. (2016). Caffeine as a Gelator. Gels, 2 (1), 9. doi:10.3390/gels2010009
© Nonappa & Kolehmainen, 2016. This is an open access article distributed under the Creative Commons Attribution License (CC BY).
Caffeine (a stimulant) and ethanol (a depressant) may have opposite effects in our body, but under in vitro conditions they can “gel” together. Caffeine, being one of the widely used stimulants, continued to surprise the scientific community with its unprecedented biological, medicinal and physicochemical properties. Here, we disclose the supramolecular self-assembly of anhydrous caffeine in a series of alcoholic and aromatic solvents, rendering a highly entangled microcrystalline network facilitating the encapsulation of the solvents as illustrated using direct imaging, microscopy analysis and NMR studies.