Closely Related Archaeal Haloarcula hispanica Icosahedral Viruses HHIV-2 and SH1 Have Nonhomologous Genes Encoding Host Recognition Functions
Jaakkola, S., Penttinen, R., Vilen, S., Jalasvuori, M., Rönnholm, G., Bamford, J., Bamford, D., & Oksanen, H. (2012). Closely Related Archaeal Haloarcula hispanica Icosahedral Viruses HHIV-2 and SH1 Have Nonhomologous Genes Encoding Host Recognition Functions. Journal of Virology, 86(9), 4734-4742. https://doi.org/10.1128/JVI.06666-11
Julkaistu sarjassa
Journal of VirologyTekijät
Päivämäärä
2012Oppiaine
Solu- ja molekyylibiologiaBiologisten vuorovaikutusten huippututkimusyksikköCell and Molecular BiologyCentre of Excellence in Biological Interactions ResearchTekijänoikeudet
© 2012, American Society for Microbiology. Published in this repository with the kind permission of the publisher.
Studies on viral capsid architectures and coat protein folds have revealed the evolutionary lineages of viruses branching to all
three domains of life. A widespread group of icosahedral tailless viruses, the PRD1-adenovirus lineage, was the first to be established.
A double -barrel fold for a single major capsid protein is characteristic of these viruses. Similar viruses carrying genes
coding for two major capsid proteins with a more complex structure, such as Thermus phage P23-77 and haloarchaeal virus SH1,
have been isolated. Here, we studied the host range, life cycle, biochemical composition, and genomic sequence of a new isolate,
Haloarcula hispanica icosahedral virus 2 (HHIV-2), which resembles SH1 despite being isolated from a different location. Comparative
analysis of these viruses revealed that their overall architectures are very similar except that the genes for the receptor
recognition vertex complexes are unrelated even though these viruses infect the same hosts.
Julkaisija
American Society for MicrobiologyISSN Hae Julkaisufoorumista
0022-538XAsiasanat
Julkaisu tutkimustietojärjestelmässä
https://converis.jyu.fi/converis/portal/detail/Publication/21710622
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