Serological Survey of Rodent-Borne Viruses in Finnish Field Voles
Forbes, K. M., Voutilainen, L., Jääskeläinen, A., Sironen, T., Kinnunen, P., Stuart, P., . . . Huitu, O. (2014). Serological Survey of Rodent-Borne Viruses in Finnish Field Voles. Vector-Borne and Zoonotic Diseases, 14 (4), 278-283. doi:10.1089/vbz.2013.1526
Published inVector-Borne and Zoonotic Diseases
DisciplineEkologia ja evoluutiobiologia
© 2014 Mary Ann Liebert, Inc. Publishers. This is a final draft version of an article whose final and definitive form has been published by Mary Ann Liebert, Inc. Publishers. Published in this repository with the kind permission of the publisher.
In northern Europe, rodent populations display cyclic density fluctuations, which can be correlated with the human incidence of zoonotic diseases they spread. During density peaks, field voles (Microtus agrestis) become one of the most abundant rodent species in northern Europe, yet little is known of the viruses they host. We screened 709 field voles, trapped from 14 sites over three years, for antibodies against four rodent-borne, potentially zoonotic viruses or virus groups: hantaviruses, lymphocytic choriomeningitis virus (LCMV), Ljungan virus (LV) and orthopoxviruses (OPV). Antibodies against all four viruses were detected. However, seroprevalence of hantaviruses, LV and LCMV was low. OPV antibodies (most likely cowpox) were more common but restricted geographically to southeast Finland. Within these sites, antibody prevalence showed delayed density-dependence in spring and direct density-dependence in fall. Higher seroprevalence was found in spring than fall. These results substantially increase knowledge of the presence and distribution of viruses of field voles in Finland, as well as CPXV infection dynamics. ...