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dc.contributor.authorSillanpää, Elina
dc.contributor.authorStenroth, Lauri
dc.contributor.authorBijlsma, A.Y.
dc.contributor.authorRantanen, Taina
dc.contributor.authorMcPhee, J. S.
dc.contributor.authorMaden-Wilkinson, T. M.
dc.contributor.authorJones, D. A.
dc.contributor.authorNarici, M. V.
dc.contributor.authorGapeyeva, H.
dc.contributor.authorPääsuke, M.
dc.contributor.authorBarnouin, Y.
dc.contributor.authorButler-Browne, G. S.
dc.contributor.authorMeskers, C. G.
dc.contributor.authorMaier, A. B.
dc.contributor.authorTörmäkangas, Timo
dc.contributor.authorSipilä, Sarianna
dc.date.accessioned2015-01-22T08:58:53Z
dc.date.available2015-07-30T21:45:05Z
dc.date.issued2014
dc.identifier.citationSillanpää, E., Stenroth, L., Bijlsma, A.Y., Rantanen, T., McPhee, J. S., Maden-Wilkinson, T. M., Jones, D. A., Narici, M. V., Gapeyeva, H., Pääsuke, M., Barnouin, Y., Butler-Browne, G. S., Meskers, C. G., Maier, A. B., Törmäkangas, T., & Sipilä, S. (2014). Associations between muscle strength, spirometric pulmonary function and mobility in healthy older adults. <i>Age</i>, <i>36</i>(4), Article 9667. <a href="https://doi.org/10.1007/s11357-014-9667-7" target="_blank">https://doi.org/10.1007/s11357-014-9667-7</a>
dc.identifier.otherCONVID_23770298
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/45141
dc.description.abstractBackground: Pathological obstruction in lungs leads to severe decreases in muscle strength and mobility in patients suffering from chronic obstructive pulmonary disease. The purpose of this study was to investigate the interdependency between muscle strength, spirometric pulmonary functions and mobility outcomes in healthy older men and women, where skeletal muscle and pulmonary function decline without interference of overt disease. Methods: 135 69 to 81‐yr‐old participants were recruited into the cross‐sectional study, which was performed as a part of European study MyoAge. Full, partial and no mediation models were constructed to assess the interdependency between muscle strength (handgrip strength, knee extension torque, lower extremity muscle power), spirometric pulmonary function (FVC, FEV1 and FEF50) and mobility (6‐min walk and Timed Up and Go tests). The models were adjusted for age, sex, total fat mass, body height and site of enrolment.   Results: Partial mediation models, indicating both direct and pulmonary function mediated associations between muscle strength and mobility, fitted best to the data. Greater handgrip strength was significantly associated with higher FVC, FEV1 and FEF50 (p<0.05). Greater muscle power was significantly associated with better performance in mobility tests. Conclusions: Results suggest that decline in mobility with aging may be caused by decreases in both muscle strength and power, but also mediated through decreases in spirometric pulmonary function. Future longitudinal studies are warranted to better understand how loss of function and mass of the respiratory muscles will affect pulmonary function among older people and how these changes are linked to mobility decline.
dc.language.isoeng
dc.publisherSpringer Netherlands; American Aging Association
dc.relation.ispartofseriesAge
dc.subject.otherhandgrip strength
dc.subject.otherknee extension torque
dc.subject.otherlower extremity muscle power
dc.subject.othersix-minute walk test
dc.subject.otherspirometric pulmonary function
dc.subject.othertimed up and go test
dc.titleAssociations between muscle strength, spirometric pulmonary function and mobility in healthy older adults
dc.typeresearch article
dc.identifier.urnURN:NBN:fi:jyu-201501191141
dc.contributor.laitosLiikuntabiologian laitosfi
dc.contributor.laitosTerveystieteiden laitosfi
dc.contributor.laitosDepartment of Biology of Physical Activityen
dc.contributor.laitosDepartment of Health Sciencesen
dc.contributor.oppiaineBiomekaniikkafi
dc.contributor.oppiaineGerontologia ja kansanterveysfi
dc.contributor.oppiaineGerontologian tutkimuskeskusfi
dc.contributor.oppiaineHyvinvoinnin tutkimuksen yhteisöfi
dc.contributor.oppiaineBiomechanicsen
dc.contributor.oppiaineGerontology and Public Healthen
dc.contributor.oppiaineGerontology Research Centeren
dc.contributor.oppiaineSchool of Wellbeingen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2015-01-19T16:30:03Z
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.relation.issn0161-9152
dc.relation.numberinseries4
dc.relation.volume36
dc.type.versionacceptedVersion
dc.rights.copyright© American Aging Association 2014. This is an author's final draft version of an article whose final and definitive form has been published by American Aging Association (Springer). Published in this repository with the kind permission of the publisher.
dc.rights.accesslevelopenAccessfi
dc.type.publicationarticle
dc.subject.ysospirometria
jyx.subject.urihttp://www.yso.fi/onto/yso/p9036
dc.relation.doi10.1007/s11357-014-9667-7
dc.type.okmA1


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