| dc.contributor.author | Ylilauri, Mikko | |
| dc.date.accessioned | 2014-01-20T08:08:05Z | |
| dc.date.available | 2014-01-20T08:08:05Z | |
| dc.date.issued | 2014 | |
| dc.identifier.isbn | 978-951-39-5583-0 | |
| dc.identifier.other | oai:jykdok.linneanet.fi:1291269 | |
| dc.identifier.uri | https://jyx.jyu.fi/handle/123456789/42819 | |
| dc.format.extent | 1 verkkoaineisto (61, [15] sivua) | |
| dc.language.iso | eng | |
| dc.publisher | University of Jyväskylä | |
| dc.relation.ispartofseries | Jyväskylä studies in biological and environmental science | |
| dc.relation.haspart | <b>Article I:</b> Postila P.A., Ylilauri M. & Pentikäinen O.T. 2011. Full and partial agonism of ionotropic glutamate receptors indicated by molecular dynamics simulations. <i>Journal of Chemical Information and Modeling 51: 1037–1047. </i> <a href=" http://dx.doi.org/ 10.1021/ci2000055 ">DOI: 10.1021/ci2000055 </a> | |
| dc.relation.haspart | <b>Article II:</b> Ylilauri M. & Pentikäinen O.T. 2012. Structural mechanism of N-methyl-D -aspartate receptor type 1 partial agonism. <i>PLoS One 7 (10): e47604. </i><a href=" http://dx.doi.org/ 10.1371/journal.pone.0047604. ">DOI: 10.1371/journal.pone.0047604 </a> | |
| dc.relation.haspart | <b>Article III:</b> Ylilauri M. & Pentikäinen O.T. 2013. MMGBSA as a tool to understand the binding affinities of filamin-peptide interactions. <i>Journal of Chemical Information and Modeling 53: 2626-2633 </i><a href=" http://dx.doi.org/ 10.1021/ci4002475">. DOI: 10.1021/ci4002475 </a> | |
| dc.relation.haspart | <b>Article IV:</b> Ylilauri M., Mattila E., Nurminen E.M., Käpylä J., Niinivehmas S.P., Määttä J.A., Pentikäinen U., Ivaska J. & Pentikäinen O.T. 2013. Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone. <i>Biochimica et Biophysica Acta 1834: 1988-1997</i>. <a href=" http://dx.doi.org/ 10.1016/j.bbapap.2013.07.001 ">DOI: 10.1016/j.bbapap.2013.07.001 </a> | |
| dc.subject.other | tietokonesimulointi | |
| dc.subject.other | molekyylidynamiikka | |
| dc.subject.other | ionotrooppiset glutamaattireseptorit | |
| dc.subject.other | peptidiligandit | |
| dc.subject.other | iGluR | |
| dc.subject.other | FLNa | |
| dc.subject.other | TCPTP | |
| dc.subject.other | binding free energy | |
| dc.subject.other | filamin | |
| dc.subject.other | ionotropic glutamate receptor | |
| dc.subject.other | molecular dynamics | |
| dc.subject.other | T-cell protein tyrosine phosphatase | |
| dc.title | Effect of ligand-binding on protein function | |
| dc.type | Diss. | |
| dc.identifier.urn | URN:ISBN:978-951-39-5583-0 | |
| dc.type.dcmitype | Text | en |
| dc.type.ontasot | Väitöskirja | fi |
| dc.type.ontasot | Doctoral dissertation | en |
| dc.contributor.tiedekunta | Matemaattis-luonnontieteellinen tiedekunta | fi |
| dc.contributor.tiedekunta | Faculty of Mathematics and Science | en |
| dc.contributor.yliopisto | University of Jyväskylä | en |
| dc.contributor.yliopisto | Jyväskylän yliopisto | fi |
| dc.contributor.oppiaine | Solu- ja molekyylibiologia | fi |
| dc.relation.issn | 1456-9701 | |
| dc.relation.numberinseries | 272 | |
| dc.rights.accesslevel | openAccess | fi |
| dc.subject.yso | proteiinit | |
| dc.subject.yso | ligandit | |
| dc.subject.yso | filamiinit | |
| dc.subject.yso | sitoutuminen | |
| dc.subject.yso | lääkesuunnittelu | |
| dc.subject.yso | laskennallinen tiede | |
| dc.subject.yso | simulointi | |
| dc.subject.yso | laskennalliset menetelmät | |
