Näytetään aineistoja, joilla on samankaltainen nimeke tai asiasanat.

• G2/M checkpoint regulation and apoptosis facilitate the nuclear egress of parvoviral capsids 

  Mattola, Salla; Mäntylä, Elina; Aho, Vesa; Salminen, Sami; Leclerc, Simon; Oittinen, Mikko; Salokas, Kari; Järvensivu, Jani; Hakanen, Satu; Ihalainen, Teemu O.; Viiri, Keijo; Vihinen-Ranta, Maija (Frontiers Media SA, 2022)

  The nuclear export factor CRM1-mediated pathway is known to be important for the nuclear egress of progeny parvovirus capsids in the host cells with virus-mediated cell cycle arrest at G2/M. However, it is still unclear ...

• Effect of ovarian hormones on microRNA signaling in response to acute bout of exercise in female rats : focus on extracellular vesicles as signal carrier 

  Maja, Anni (2024)

  Menopaussi voi aiheuttaa naisille negatiivisia muutoksia terveyteen. Menopaussin aikaisella liikuntaharjoittelulla on todettu olevan positiivinen vaikutus terveysvaivoihin, mutta yksin se ei riitä estämään terveydessä ...

• Acetic Acid Mediated for One-Pot Synthesis of Novel Pyrazolyl s-Triazine Derivatives for the Targeted Therapy of Triple-Negative Breast Tumor Cells (MDA-MB-231) via EGFR/PI3K/AKT/mTOR Signaling Cascades 

  Shawish, Ihab; Barakat, Assem; Aldalbahi, Ali; Alshaer, Walhan; Daoud, Fadwa; Alqudah, Dana A.; Al Zoubi, Mazhar; Hatmal, Ma’mon M.; Nafie, Mohamed S.; Haukka, Matti; Sharma, Anamika; de la Torre, Beatriz G.; Albericio, Fernando; El-Faham, Ayman (MDPI AG, 2022)

  Here, we described the synthesis of novel pyrazole-s-triazine derivatives via an easy one-pot procedure for the reaction of β-dicarbonyl compounds (ethylacetoacetate, 5,5-dimethyl-1,3-cyclohexadione or 1,3-cyclohexadionone) ...

• Activation of p53 signaling and regression of breast and prostate carcinoma cells by spirooxindole-benzimidazole small molecules 

  Barakat, Assem; Alshahrani, Saeed; Al-Majid, Abdullah Mohammed; Alamary, Abdullah Saleh; Haukka, Matti; Abu-Serie, Marwa, M.; Dömling, Alexander; Domingo, Luis, R.; Elshaier, Yaseen A. M. M. (Frontiers Media SA, 2024)

  This study discusses the synthesis and use of a new library of spirooxindole-benzimidazole compounds as inhibitors of the signal transducer and activator of p53, a protein involved in regulating cell growth and cancer ...

• PROX1 transcription factor controls rhabdomyosarcoma growth, stemness, myogenic properties and therapeutic targets 

  Gizaw, Nebeyu Yosef; Kallio, Pauliina; Punger, Tatjana; Gucciardo, Erika; Haglund, Caj; Böhling, Tom; Lehti, Kaisa; Sampo, Mika; Alitalo, Kari; Kivelä, Riikka (National Academy of Sciences, 2022)

  Rhabdomyosarcoma (RMS) is an aggressive pediatric soft-tissue cancer with features of skeletal muscle. Because of poor survival of RMS patients and severe long-term side effects of RMS therapies, alternative RMS therapies ...