Showing items with similar title or keywords.

• Does breast carcinoma belong to the Lynch syndrome tumor spectrum? : Somatic mutational profiles vs. ovarian and colorectal carcinomas 

  Porkka, Noora K.; Olkinuora, Alisa; Kuopio, Teijo; Ahtiainen, Maarit; Eldfors, Samuli; Almusa, Henrikki; Mecklin, Jukka-Pekka; Peltomäki, Päivi (Impact Journals LLC, 2020)

  Inherited DNA mismatch repair (MMR) defects cause predisposition to colorectal, endometrial, ovarian, and other cancers occurring in Lynch syndrome (LS). It is unsettled whether breast carcinoma belongs to the LS tumor ...

• Validation of the breast cancer Analysis Protocol Packages (APPs) for the determination of estrogen and progesterone receptors (ER, PR), human epidermal growth factor recep- tor 2 (HER2) and proliferation index (Ki67) in breast cancer 

  Heikinmäki, Nella (2022)

  Rintasyöpä on naisten yleisin syöpä maailmassa. Sillä on merkittävä vaikutus kansanterveyteen sekä yhteiskuntaan ja tämän vuoksi sitä on tutkittu laajasti jo pitkään. Tämän opinnäytetyön tarkoituksena on validoida kaupallisen ...

• Composition and prognostic significance of T helper lymphocytes in lung cancer 

  Kivelä, Essi (2024)

  Lung cancer is the most fatal cancer worldwide with non-small cell lung cancer and its subtypes adenocarcinoma and squamous cell carcinoma accounting for approximately 80% of all lung cancer cases. In lung cancer treatment ...

• Activation of p53 signaling and regression of breast and prostate carcinoma cells by spirooxindole-benzimidazole small molecules 

  Barakat, Assem; Alshahrani, Saeed; Al-Majid, Abdullah Mohammed; Alamary, Abdullah Saleh; Haukka, Matti; Abu-Serie, Marwa, M.; Dömling, Alexander; Domingo, Luis, R.; Elshaier, Yaseen A. M. M. (Frontiers Media SA, 2024)

  This study discusses the synthesis and use of a new library of spirooxindole-benzimidazole compounds as inhibitors of the signal transducer and activator of p53, a protein involved in regulating cell growth and cancer ...

• Discovery of Potent Indolyl-Hydrazones as Kinase Inhibitors for Breast Cancer : Synthesis, X-ray Single-Crystal Analysis, and In Vitro and In Vivo Anti-Cancer Activity Evaluation 

  Salama, Eid E.; Youssef, Mohamed F.; Aboelmagd, Ahmed; Boraei, Ahmed T. A.; Nafie, Mohamed S.; Haukka, Matti; Barakat, Assem; Sarhan, Ahmed A. M. (MDPI AG, 2023)

  According to data provided by the World Health Organization (WHO), a total of 2.3 million women across the globe received a diagnosis of breast cancer in the year 2020, and among these cases, 685,000 resulted in fatalities. ...