Atovakonin, parvakonin ja buparvakonin syntetiikka, rakennemääritys sekä lääketieteellinen käyttö
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Understanding selective reduction reactions with heterogeneous Pd and Pt : climbing out of the black box
Tuokko, Sakari (University of Jyväskylä, 2016) -
Synthesis of an antiaromatic circulenophane
Pazhouhan Fekri, Afra (2020)Otherwise unstable antiaromatic compounds can be studied when they are integrated into a bigger π-conjugated system. Cyclooctatetraene (COT) compounds are easy to synthesize and study, but they reside in a non-planar ... -
Stereoselective Synthesis of Spiro-Decalin Oxindole Derivatives via Sequential Organocatalytic Michael-Domino Michael/Aldol Reaction
Straminelli, Leonardo; Vicentini, Francesco; Di Sabato, Antonio; Montone, Carmela Maria; Cavaliere, Chiara; Rissanen, Kari; Leonelli, Francesca; Vetica, Fabrizio (American Chemical Society (ACS), 2022)A highly stereoselective procedure for the synthesis of spiro-polycyclic oxindoles bearing five contiguous stereogenic centers including two tetrasubstituted carbons has been developed. Under sequential organocatalysis ... -
Tributyl(1-((dimethylamino)(dimethyliminio)methyl)-1,4-dihydropyridin-4-yl)phosphonium Ditrifluoromethanesulfonate
Gong, Yiwei; Ward, Jas S.; Rissanen, Kari; Mulks, Florian F. (MDPI AG, 2023)Site-selective functionalization of pyridines is a crucial tool for the synthesis of diverse pharmaceuticals and materials. We introduced diiminium pyridine adducts as highly convenient and potent Lewis acids. We report ... -
Asymmetric Synthesis of Dihydropyranones with Three Contiguous Stereocenters by an NHC‐Catalyzed Kinetic Resolution
Axelsson, Anton; Westerlund, Mathias; Zacharias, Savannah C.; Runemark, August; Haukka, Matti; Sundén, Henrik (Wiley, 2021)An oxidative NHC-catalyzed kinetic resolution (KR) of racemic mixtures is presented. The developed reaction furnishes tricyclic dihydropyranones with three contiguous stereocenters in excellent dia- and enantioselectivity, ...