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The effect of a temperature‐sensitive prophage on the evolution of virulence in an opportunistic bacterial pathogen
(Wiley, 2022)
Viruses are key actors of ecosystems and have major impacts on global biogeochemical cycles. Prophages deserve particular attention as they are ubiquitous in bacterial genomes and can enter a lytic cycle when triggered by ...
Distinctive Evasion Mechanisms to Allow Persistence of Borrelia burgdorferi in Different Human Cell Lines
(Frontiers Research Foundation, 2021)
Lyme borreliosis is a multisystemic disease caused by the pleomorphic bacteria of the Borrelia burgdorferi sensu lato complex. The exact mechanisms for the infection to progress into a prolonged sequelae of the disease are ...
SARS-CoV-2-virus Jyväskylässä jätevesiseurannan perusteella
(2022)
Maaliskuusta 2020 lähtien SARS-CoV-2-virus on ollut osana jokaisen ihmisen
arkipäivää. Pandemian aikana virus on muuntunut uusiksi virusvarianteiksi,
jotka ovat vuorollaan olleet aikansa valtavariantteja. Pandemian ...
Keltatulkku, valaslintu ja laulukotka : lintujen lajitunnistus alakoulussa
(2013)
Alakoululaisten lintujen lajitunnistustaidot sekä oppilaiden asenteet lintujen tunnistamiseen ja tunnistamiseen tarvittavan tiedon hankkimistavat olivat tämän pro gradu – tutkimuksen kohteena. Tutkimukseen valittiin kolme ...
On dynamics of parvoviral replication protein NS1
(University of Jyväskylä, 2010)
Woodland key habitats : a key to effective conservation of forest biodiversity?
(University of Jyväskylä, 2011)
Virus persistence on surfaces : studies on nature-based solutions
(Jyväskylän yliopisto, 2024)
The emergence of new viruses is always a global health threat, as they have the potential to cause widespread outbreaks. Viruses can spread through direct transmission but also via contaminated surfaces. The recent COVID-19 pandemic, in particular, highlighted the importance of maintaining clean public spaces to minimize the transmission risk through surfaces. While surface disinfection remains a practical solution, it can be laborious, time-consuming, costly, and environmentally harmful. This dissertation has examined nature-derived antiviral surface solutions to complement traditional strategies. Six wood species were investigated for their antiviral properties in the first study. Most of the wood species displayed broad-spectrum antiviral activity, with varying capacities to inactivate both enveloped and non-enveloped viruses. The antiviral efficacy of wood was hypothesized to be attributed to its porous nature and the presence of wood extractives. The second study evaluated the efficacy of a tall oil rosin-functionalized plastic surface against coronaviruses. The active component rosin rapidly reduced the infectivity of both seasonal human coronavirus OC43 and SARS-CoV-2 without apparent changes in the virion structure, as evidenced by different imaging techniques. The third study demonstrated that polyphenols have potent antiviral activity against different serotypes of enteroviruses. The efficacy of these polyphenols significantly increased when functionalized on the surface of gold nanoparticles. The antiviral activity is hypothesized to be associated with their ability to bind to multiple sites on the capsid. This interaction may result in the super stabilization of the virion, preventing the virus's binding to its host cells....
Viime vuosina virukset ovat aiheuttaneet merkittäviä maailmanlaajuisia terveysuhkia, koska ne voivat aiheuttaa laajoja epidemioita. Tuorein SARS-CoV-2:n aiheuttama COVID-19-pandemia on korostanut julkisten tilojen puhtauden ylläpitämisen tärkeyttä...
Viime vuosina virukset ovat aiheuttaneet merkittäviä maailmanlaajuisia terveysuhkia, koska ne voivat aiheuttaa laajoja epidemioita. Tuorein SARS-CoV-2:n aiheuttama COVID-19-pandemia on korostanut julkisten tilojen puhtauden ylläpitämisen tärkeyttä...
Perspectives on variation in species richness : area, energy and habitat heterogeneity
(University of Jyväskylä, 2011)