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Distinctive Evasion Mechanisms to Allow Persistence of Borrelia burgdorferi in Different Human Cell Lines
(Frontiers Research Foundation, 2021)
Lyme borreliosis is a multisystemic disease caused by the pleomorphic bacteria of the Borrelia burgdorferi sensu lato complex. The exact mechanisms for the infection to progress into a prolonged sequelae of the disease are ...
Borrelia burgdorferi Outer Membrane Vesicles Contain Antigenic Proteins, but Do Not Induce Cell Death in Human Cells
(MDPI AG, 2022)
Like many bacterial species, Borrelia burgdorferi, the pleomorphic bacterium that causes Lyme borreliosis, produces outer membrane vesicles (OMVs). Borrelial OMVs (BbOMVs) have been identified as containing virulence ...
Molecular pathways mediating immunosuppression in response to prolonged intensive physical training, low-energy availability, and intensive weight loss
(Frontiers Research Foundation, 2019)
Exercise and exercise-induced weight loss have a beneficial effect on overall health, including positive effects on molecular pathways associated with immune function, especially in overweight individuals. The main aim of ...
Mechanisms and elimination of Borrelia burgdorferi persistence in vitro
(Jyväskylän yliopisto, 2022)
Borrelia burgdorferi sensu lato complex are species of pleomorphic spirochete bacteria causing Lyme borreliosis (LB), the most common tick-borne disease in the Northern hemisphere. Although antibiotics usually kill the ...
Effects of high-fat diet and prebiotic fiber supplementation on hippocampal inflammation and adult neurogenesis
(2021)
Paljon energiaa sisältävän ravinnon lisääntyminen osana tavallista ruokavaliota on viimeisten vuosikymmenien aikana todettu johtavan ylipainosta aiheutuviin terveyshaittoihin ja muuttavan suolistomikrobiston rakennetta. ...
Combinatorial and independent effects of exercise and myostatin/activin blocking on muscle gene expression profiling
(2013)
The administration of soluble ligand binding domain of type IIb activin receptor fused
to the Fc domain (sActRIIB-Fc) has been recently shown to attenuate dystrophic
pathology and to increase muscle mass, but also to supress ...
Cognitive and physical functions among middle-aged and older people: A special emphasis on executive functions and walking
(Jyväskylän yliopisto, 2023)
Cognitive and physical functions are key factors for safe walking. Unfortunately, these functions deteriorate with age and therefore older adults may experience difficulties in outdoor mobility. In women, decline in cognitive ...
Steroid conjugates for applications in pharmacology and biology
(2011)
The scope of present study is rather broad and may seem to be non-uniform, covering subjects such as the treatment of insect pest species and atherosclerosis. Nevertheless, the magic word "steroid" connects the presented ...
Cross-species transcriptomic analysis elucidates constitutive aryl hydrocarbon receptor activity
(BioMed Central Ltd., 2014)
Background.
Research on the aryl hydrocarbon receptor (AHR) has largely focused on variations in toxic outcomes resulting from its activation by halogenated aromatic hydrocarbons. But the AHR also plays key roles in ...
Big vs powerful : molecular signalling responses to hypertrophic and power resistance exercise modalities
(2015)
Introduction: The effects of resistance exercise (RE) loading on molecular signalling proteins, including those involved in protein translation and thus skeletal muscle hypertrophy have been extensively studied. However, ...