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Borrelia burgdorferi Outer Membrane Vesicles Contain Antigenic Proteins, but Do Not Induce Cell Death in Human Cells
(MDPI AG, 2022)
proteins (Osps) A, B, and C, as well as DNA. However, the pathogenicity of BbOMVs in disease development is still unclear. In this study, we characterized purified BbOMVs by analyzing their size and immunolabeling for known antigenic markers: OspA, OspC, p...
Mechanisms and elimination of Borrelia burgdorferi persistence in vitro
(Jyväskylän yliopisto, 2022)
colocalisation during the nine days of coculture. BbOMVs were on average 33 nm in diameter and contained antigenic proteins OspA, OspC, p39 and peptidoglycan, as well as double stranded DNA. However, the vesicles did not induce cell death after 72-h of coculture...
Molecular pathways mediating immunosuppression in response to prolonged intensive physical training, low-energy availability, and intensive weight loss
(Frontiers Research Foundation, 2019)
Exercise and exercise-induced weight loss have a beneficial effect on overall health, including positive effects on molecular pathways associated with immune function, especially in overweight individuals. The main aim of ...
Requirements for artificial intelligence used for the diagnosis of the COVID-19 from chest X-rays
(2022)
Viime aikoina on julkaistu useita tekoälymalleja COVID-19 diagnosoimiseen keuhkoröntgenkuvista. Valitettavasti useiden arvioiden perusteella niissä on ongelmia jotka tekevät ne käyttökelvottomiksi kliinisessä työssä. Tässä ...
On dynamics of parvoviral replication protein NS1
(University of Jyväskylä, 2010)
Immunocompetence and sexual selection in insects
(2002)
Males of many species have extravagant morphological and behavioral secondary sexual traits, and female choice of mates is often based on these traits. It has been postulated that such traits are reliable indicators of ...
Characterizing the bacterial fish pathogen Flavobacterium columnare, and some factors affecting its pathogenicity
(University of Jyväskylä, 2010)
Flavobacterium columnare is a bacterial pathogen of fresh water fish causing lethal columnaris disease worldwide. At Finnish fish farms, columnaris disease has occurred since the early 1980s, and is a serious problem in ...
Distinctive Evasion Mechanisms to Allow Persistence of Borrelia burgdorferi in Different Human Cell Lines
(Frontiers Research Foundation, 2021)
Lyme borreliosis is a multisystemic disease caused by the pleomorphic bacteria of the Borrelia burgdorferi sensu lato complex. The exact mechanisms for the infection to progress into a prolonged sequelae of the disease are ...
Parasitism, reproduction and sexual selection of roach, Rutilus rutilus L
(University of Jyväskylä, 2003)
Raine Kortetin väitöstutkimus lisää tietämystä kalan kutukyhmyistä, lisääntymisbiologiasta, seksuaalivalinnasta ja immuunipuolustuksesta. Tutkimuksessa on ensimmäistä kertaa osoitettu, että sekä loisvälitteinen että ns. ...
Condition-dependence of male sexual signalling in the drumming wolf spider Hygrolycosa rubrofasciata
(Jyväskylän yliopisto, 2003)
Jari Ahtiaisen väitöskirjatyön tutkimusten perusteella voidaan todeta, että H. rubrofasciata susihämähäkkinaaraat voivat käyttää koiraan seksuaalista kuntoa mittana arvioidessaan koiraan fenotyyppistä ja geneettistä laatua. ...