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dc.contributor.advisorStrömmer, Juho
dc.contributor.authorMannila, Heikki
dc.contributor.authorVainio, Juhani
dc.date.accessioned2020-01-13T08:10:19Z
dc.date.available2020-01-13T08:10:19Z
dc.date.issued2019
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/67201
dc.description.abstractAgeing manifests at least on the levels of structural degradation of the brain, as well as a slight cognitive decline even in healthy older adults. It is widely recognized that better physical fitness helps preserve cognitive abilities in older age and delay the inevitable cognitive decline. In this follow-up study, we investigated in what relation cognitive abilities, physical fitness and event-related potentials (ERPs) develop over approximately five years, and whether the development of cognitive abilities is possible to be predicted with the baseline of physical fitness or the ERPs. Out of the 90 older women who participated in the baseline measurement, 35 participated in this follow-up. We measured ageing-sensitive ERPs with an electroencephalography (EEG) to either somatosensory tactile stimulation or auditory sinusoidal sound stimulation. To assess the participants’ cognitive capacity, we conducted a battery of neuropsychological tests that assessed cognitive domains sensitive to ageing. In addition to these, the participants carried out a six-minute walk test to measure their aerobic physical fitness. The somatosensory P3a and the auditory P2 showed significant change over time, which reflects their ageing-sensitive nature. Decreased six-minute walk test distance was associated with a decline in explicit memory. The enlargement of the auditory P2 standard response associated with improved explicit memory, indicating neural compensation. In addition, the enlargement of the deviant response of the auditory P2 associated with worsened six-minute walk test performance. Attenuation of the deviant response of the somatosensory P3a associated with a prolonged performance time in Stroop 3 test. Higher baseline of six-minute walk test performance predicted better preservation of explicit memory. Additionally, higher (more negative) baseline of the auditory N1 predicted improvement in explicit memory performance and an increase in error susceptibility. The results of this longitudinal study indicate a connection between aerobic physical fitness and explicit memory. Additionally, we got further support indicating that the auditory P2 seems to be linked to neural compensation, as activity in fronto-central topography increased as well from the baseline measurement to the follow-up. The somatosensory P3a seems to be associated to executive functions and attentional modulation. Better preservation of explicit memory was able to be predicted with the baseline of physical fitness. In addition to P2, the predicting ability of N1 on cognitive preservation may reflect neural compensation in older adults. The results of the present study are of great importance to older adults who wish to maintain their cognitive abilities for as long as possible, and to other researchers, as valuable evidence of complicated ageing-related processes.en
dc.format.extent56
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.subject.otherevent-related potential
dc.subject.otherneuropsychological assessment
dc.subject.otherfollow-up study
dc.subject.othercognitive performance
dc.titleAgeing-related changes in cognitive functions and their associations with event-related potentials and physical fitness in healthy older adults
dc.identifier.urnURN:NBN:fi:jyu-202001131139
dc.type.ontasotPro gradu -tutkielmafi
dc.type.ontasotMaster’s thesisen
dc.contributor.tiedekuntaKasvatustieteiden ja psykologian tiedekuntafi
dc.contributor.tiedekuntaFaculty of Education and Psychologyen
dc.contributor.laitosPsykologian laitosfi
dc.contributor.laitosDepartment of Psychologyen
dc.contributor.yliopistoJyväskylän yliopistofi
dc.contributor.yliopistoUniversity of Jyväskyläen
dc.contributor.oppiainePsykologiafi
dc.contributor.oppiainePsychologyen
dc.rights.copyrightJulkaisu on tekijänoikeussäännösten alainen. Teosta voi lukea ja tulostaa henkilökohtaista käyttöä varten. Käyttö kaupallisiin tarkoituksiin on kielletty.fi
dc.rights.copyrightThis publication is copyrighted. You may download, display and print it for Your own personal use. Commercial use is prohibited.en
dc.type.publicationmasterThesis
dc.contributor.oppiainekoodi202
dc.subject.ysoikääntyminen
dc.subject.ysofyysinen kunto
dc.subject.ysoageing
dc.subject.ysophysical fitness
dc.format.contentfulltext
dc.type.okmG2


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