Auditory cortical and hippocampal local-field potentials to frequency deviant tones in urethane-anesthetized rats: An unexpected role of the sound frequencies themselves
Ruusuvirta, T., Lipponen, A., Pellinen, E.-K., Penttonen, M., & Astikainen, P. (2015). Auditory cortical and hippocampal local-field potentials to frequency deviant tones in urethane-anesthetized rats: An unexpected role of the sound frequencies themselves. International Journal of Psychophysiology, 96(3), 134–140. https://doi.org/10.1016/j.ijpsycho.2015.04.007
Published inInternational Journal of Psychophysiology
DisciplinePsykologiaMonitieteinen aivotutkimuskeskusPsychologyCentre for Interdisciplinary Brain Research
© 2015 Elsevier B.V. All rights reserved. This is a final draft version of an article whose final and definitive form has been published by Elsevier. Published in this repository with the kind permission of the publisher.
The human brain can automatically detect auditory changes, as indexed by the mismatch negativity of event-related potentials. The mechanisms that underlie this response are poorly understood. We recorded primary auditory cortical and hippocampal (dentate gyrus, CA1) local-field potentials to serial tones in urethane-anesthetized rats. In an oddball condition, a rare (deviant) tone (p = 0.11) randomly replaced a repeated (standard) tone. The deviant tone was either lower (2200, 2700, 3200, 3700 Hz) or higher (4300, 4800, 5300, 5800 Hz) in frequency than the standard tone (4000 Hz). In an equiprobability control condition, all nine tones were presented at random (p = 0.11). Differential responses to deviant tones relative to the standard tone were found in the auditory cortex and the dentate gyrus but not in CA1. Only in the dentate gyrus, the responses were found to be standard- (i.e., oddball condition-) specific. In the auditory cortex, the sound frequencies themselves sufficed to explain their generation. These findings tentatively suggest dissociation among non-contextual afferent, contextual afferent and auditory change detection processes. Most importantly, they remind us about the importance of strict control of physical sound features in mismatch negativity studies in animals. ...
PublisherElsevier BV; International Organization of Psychophysiology
Publication in research information system
MetadataShow full item record
Showing items with similar title or keywords.
Auditory cortical and hippocampal-system mismatch responses to duration deviants in urethane-anesthetized rats Ruusuvirta, Timo; Lipponen, Arto; Pellinen, Eeva; Penttonen, Markku; Astikainen, Piia (Public Library of Science, 2013-04-05)Any change in the invariant aspects of the auditory environment is of potential importance. The human brain preattentively or automatically detects such changes. The mismatch negativity (MMN) of event-related potentials ...
Yang, Tiantian; Hämäläinen, Jarmo; Lohvansuu, Kaisa; Lipponen, Arto; Penttonen, Markku; Astikainen, Piia (Elsevier, 2021)Mismatch negativity (MMN), which is an electrophysiological response demonstrated in humans and animals, reflects memory-based deviance detection in a series of sounds. However, only a few studies on rodents have used ...
Lipponen, Arto; Kurkela, Jari; Kyläheiko, I.; Hölttä, S.; Ruusuvirta, T.; Hämäläinen, Jarmo; Astikainen, Piia (Wiley-Blackwell Publishing Ltd., 2019)Spectrotemporally complex sounds carry important information for acoustic communication. Among the important features of these sounds is the temporal duration. An event‐related potential called mismatch negativity indexes ...
Astikainen, Piia; Mällo, Tanel; Ruusuvirta, Timo; Näätänen, Risto (Frontiers Research Foundation, 2014)Human infants are able to detect changes in grammatical rules in a speech sound stream. Here, we tested whether rats have a comparable ability by using an electrophysiological measure that has been shown to reflect higher ...
Kyläheiko, Iiris (2017)Ihmisaivot ovat taipuvaiset havaitsemaan muutoksia kuuloympäristössään. Elektrofysiologisissa mittauksissa tämän automaattisen muutoksen havaitsemisen merkkinä voidaan käyttää poikkeavuusnegatiivisuutta (MMN), joka on ...