Showing items with similar title or keywords.

• Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk 

  Shrine, Nick; Izquierdo, Abril G.; Chen, Jing; Packer, Richard; Hall, Robert J.; Guyatt, Anna L.; Batini, Chiara; Thompson, Rebecca J.; Pavuluri, Chandan; Malik, Vidhi; Hobbs, Brian D.; Moll, Matthew; Kim, Wonji; Tal-Singer, Ruth; Bakke, Per; Fawcett, Katherine A.; John, Catherine; Coley, Kayesha; Piga, Noemi Nicole; Pozarickij, Alfred; Lin, Kuang; Millwood, Iona Y.; Chen, Zhengming; Li, Liming; Wijnant, Sara R. A.; Lahousse, Lies; Brusselle, Guy; Uitterlinden, Andre G.; Manichaikul, Ani; Oelsner, Elizabeth C.; Rich, Stephen S.; Barr, R. Graham; Kerr, Shona M.; Vitart, Veronique; Brown, Michael R.; Wielscher, Matthias; Imboden, Medea; Jeong, Ayoung; Bartz, Traci M.; Gharib, Sina A.; Flexeder, Claudia; Karrasch, Stefan; Gieger, Christian; Peters, Annette; Stubbe, Beate; Hu, Xiaowei; Ortega, Victor E.; Meyers, Deborah A.; Bleecker, Eugene R.; Gabriel, Stacey B.; Gupta, Namrata; Smith, Albert Vernon; Luan, Jian’an; Zhao, Jing-Hua; Hansen, Ailin F.; Langhammer, Arnulf; Willer, Cristen; Bhatta, Laxmi; Porteous, David; Smith, Blair H.; Campbell, Archie; Sofer, Tamar; Lee, Jiwon; Daviglus, Martha L.; Yu, Bing; Lim, Elise; Xu, Hanfei; O’Connor, George T.; Thareja, Gaurav; Albagha, Omar M. E.; Ismail, Said I.; Al-Muftah, Wadha; Badji, Radja; Mbarek, Hamdi; Darwish, Dima; Fadl, Tasnim; Yasin, Heba; Ennaifar, Maryem; Abdellatif, Rania; Alkuwari, Fatima; Alvi, Muhammad; Al-Sarraj, Yasser; Saad, Chadi; Althani, Asmaa; Fethnou, Eleni; Qafoud, Fatima; Alkhayat, Eiman; Afifi, Nahla; Tomei, Sara; Liu, Wei; Lorenz, Stephan; Syed, Najeeb; Almabrazi, Hakeem; Vempalli, Fazulur Rehaman; Temanni, Ramzi; Saqri Tariq, Abu; Khatib, Mohammedhusen; Hamza, Mehshad; Zaid Tariq, Abu; El Khouly, Ahmed; Pathare, Tushar; Poolat, Shafeeq; Al-Ali, Rashid; Al-Khodor, Souhaila; Alshafai, Mashael; Badii, Ramin; Chouchane, Lotfi; Estivill, Xavier; Fakhro, Khalid; Mokrab, Younes; Puthen, Jithesh V.; Tatari, Zohreh; Suhre, Karsten; Granell, Raquel; Faquih, Tariq O.; Hiemstra, Pieter S.; Slats, Annelies M.; Mullin, Benjamin H.; Hui, Jennie; James, Alan; Beilby, John; Patasova, Karina; Hysi, Pirro; Koskela, Jukka T.; Wyss, Annah B.; Jin, Jianping; Sikdar, Sinjini; Lee, Mikyeong; May-Wilson, Sebastian; Pirastu, Nicola; Kentistou, Katherine A.; Joshi, Peter K.; Timmers, Paul R. H. J.; Williams, Alexander T.; Free, Robert C.; Wang, Xueyang; Morrison, John L.; Gilliland, Frank D.; Chen, Zhanghua; Wang, Carol A.; Foong, Rachel E.; Harris, Sarah E.; Taylor, Adele; Redmond, Paul; Cook, James P.; Mahajan, Anubha; Lind, Lars; Palviainen, Teemu; Lehtimäki, Terho; Raitakari, Olli T.; Kaprio, Jaakko; Rantanen, Taina; Pietiläinen, Kirsi H.; Cox, Simon R.; Pennell, Craig E.; Hall, Graham L.; Gauderman, W. James; Brightling, Chris; Wilson, James F.; Vasankari, Tuula; Laitinen, Tarja; Salomaa, Veikko; Mook-Kanamori, Dennis O.; Timpson, Nicholas J.; Zeggini, Eleftheria; Dupuis, Josée; Hayward, Caroline; Brumpton, Ben; Langenberg, Claudia; Weiss, Stefan; Homuth, Georg; Schmidt, Carsten Oliver; Probst-Hensch, Nicole; Jarvelin, Marjo-Riitta; Morrison, Alanna C.; Polasek, Ozren; Rudan, Igor; Lee, Joo-Hyeon; Sayers, Ian; Rawlins, Emma L.; Dudbridge, Frank; Silverman, Edwin K.; Strachan, David P.; Walters, Robin G.; Morris, Andrew P.; London, Stephanie J.; Cho, Michael H.; Wain, Louise V.; Hall, Ian P.; Tobin, Martin D. (Nature Publishing Group, 2023)

  Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung function to date, comprising 580,869 ...

• Rare variant analyses across multiethnic cohorts identify novel genes for refractive error 

  Musolf, Anthony M.; Haarman, Annechien E. G.; Luben, Robert N.; Ong, Jue-Sheng; Patasova, Karina; Trapero, Rolando Hernandez; Marsh, Joseph; Jain, Ishika; Jain, Riya; Wang, Paul Zhiping; Lewis, Deyana D.; Tedja, Milly S.; Iglesias, Adriana I.; Li, Hengtong; Cowan, Cameron S.; Baird, Paul Nigel; Veluchamy, Amutha Barathi; Burdon, Kathryn P.; Campbell, Harry; Chen, Li Jia; Cheng, Ching-Yu; Chew, Emily Y.; Craig, Jamie E.; Cumberland, Phillippa M.; Deangelis, Margaret M.; Delcourt, Cécile; Ding, Xiaohu; Evans, David M.; Fan, Qiao; Fossarello, Maurizio; Foster, Paul J.; Gharahkhani, Puya; Iglesias, Adriana I.; Guggenheim, Jeremy A.; Guo, Xiaobo; Han, Xikun; He, Mingguang; Hewitt, Alex W.; Hoang, Quan V.; Iyengar, Sudha K.; Jonas, Jost B.; Kähönen, Mika; Kaprio, Jaakko; Klein, Barbara E.; Lass, Jonathan H.; Lee, Kris; Lehtimäki, Terho; Lewis, Deyana; Li, Qing; Li, Shi-Ming; Lyytikäinen, Leo-Pekka; MacGregor, Stuart; Mackey, David A.; Martin, Nicholas G.; Meguro, Akira; Middlebrooks, Candace; Miyake, Masahiro; Mizuki, Nobuhisa; Musolf, Anthony; Nickels, Stefan; Oexle, Konrad; Pang, Chi Pui; Paterson, Andrew D.; Pennell, Craig; Pfeiffer, Norbert; Polasek, Ozren; Rahi, Jugnoo S.; Raitakari, Olli; Rudan, Igor; Sahebjada, Srujana; Simpson, Claire L.; Tai, E-Shyong; Tedja, Milly S.; Tideman, J. Willem L.; Tsujikawa, Akitaka; Wang, Ningli; Bin, Wei Wen; Williams, Cathy; Williams, Katie M.; Wilson, James F.; Wojciechowski, Robert; Wang, Ya Xing; Yamashiro, Kenji; Yam, Jason C. S.; Yap, Maurice K. H.; Yazar, Seyhan; Yip, Shea Ping; Young, Terri L.; Zhou, Xiangtian; Biino, Ginevra; Klein, Alison P.; Duggal, Priya; Mackey, David A.; Hayward, Caroline; Haller, Toomas; Metspalu, Andres; Wedenoja, Juho; Pärssinen, Olavi; Cheng, Ching-Yu; Saw, Seang-Mei; Stambolian, Dwight; Hysi, Pirro G.; Khawaja, Anthony P.; Vitart, Veronique; Hammond, Christopher J.; van Duijn, Cornelia M.; Verhoeven, Virginie J. M.; Klaver, Caroline C. W.; Bailey-Wilson, Joan E. (Nature Publishing Group, 2023)

  Refractive error, measured here as mean spherical equivalent (SER), is a complex eye condition caused by both genetic and environmental factors. Individuals with strong positive or negative values of SER require spectacles ...

• Effect of resource availability on evolution of virulence and competition in an environmentally transmitted pathogen 

  Pulkkinen, Katja; Pekkala, Nina; Ashrafi, Roghaieh; Hämäläinen, Dorrit M.; Nkembeng, Aloysius N.; Lipponen, Anssi; Hiltunen, Teppo; Valkonen, Janne; Taskinen, Jouni (Federation of European Microbiological Societies; Oxford University Press, 2018)

  Understanding ecological and epidemiological factors driving pathogen evolution in contemporary time scales is a major challenge in modern health management. Pathogens that replicate outside the hosts are subject to selection ...

• Efficient design and modeling strategies for follow-up studies with time-varying covariates 

  Reinikainen, Jaakko (University of Jyväskylä, 2015)

  Epidemiological studies can often be designed in several ways, some of which may be more optimal than others. Possible designs may differ in the required resources or the ability to provide reliable answers to the questions ...

• Underweight and obesity are related to higher mortality in patients undergoing coronary angiography : The KARDIO invasive cardiology register study 

  Laukkanen, Jari A.; Kunutsor, Setor K.; Hernesniemi, Jussi; Immonen, Jaakko; Eskola, Markku; Zaccardi, Francesco; Niemelä, Matti; Mäkikallio, Timo; Hagnäs, Magnus; Piuhola, Jarkko; Juvonen, Jukka; Sia, Jussi; Rummukainen, Juha; Kervinen, Kari; Karvanen, Juha; Nikus, Kjell; KARDIO Study Group (John Wiley & Sons, 2022)

  Background In patients with some cardiovascular disease conditions, slightly elevated body mass index (BMI) is associated with a lower mortality risk (termed “obesity paradox”). It is uncertain, however, if this obesity ...