Monimuotoisia neuronin kaltaisia soluja SH-SY5Y-solulinjasta
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Negatively Charged Gangliosides Promote Membrane Association of Amphipathic Neurotransmitters
Juhola, Hanna; Postila, Pekka; Rissanen, Sami; Lolicato, Fabio; Vattulainen, Ilpo; Róg, Tomasz (Pergamon Press, 2018)Lipophilic neurotransmitters (NTs) such as dopamine are chemical messengers enabling neurotransmission by adhering onto the extracellular surface of the post-synaptic membrane in a synapse, followed by binding to their ... -
Liikunnan ja hormonikorvaushoidon vaikutus veren HDL- ja LDL-kolesterolipitoisuuteen postmenopausaalisilla naisilla
Karppinen, Miira (2021)Kardiometabolinen terveys heikkenee naisilla menopaussin jälkeen hormonitasojen muutosten seurauksena. Riskitekijöitä sydän- ja verisuonisairauksille ovat alhainen HDL- ja korkea LDL-kolesterolipitoisuus. Vaihdevuodet eli ... -
National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio : A pooled analysis of 458 population-based studies in Asian and Western countries
NCD Risk Factor Collaboration (Oxford University Press, 2020)Background: Although high-density lipoprotein (HDL) and non-HDL cholesterol have opposite associations with coronary heart disease, multi-country reports of lipid trends only use total cholesterol (TC). Our aim was to ... -
Is low cardiorespiratory fitness a feature of metabolic syndrome in children and adults?
Haapala, Eero A.; Tompuri, Tuomo; Lintu, Niina; Viitasalo, Anna; Savonen, Kai; Lakka, Timo A.; Laukkanen, Jari A. (Elsevier, 2022)Objectives Cardiorespiratory fitness (CRF) has been inversely associated with risk of cardiometabolic diseases. However, there are no studies comparing the independent associations of CRF scaled by body size and composition ... -
Menopausal status and physical activity are independently associated with cardiovascular risk factors of healthy middle-aged women : cross-sectional and longitudinal evidence
Karvinen, Sira; Jergenson, Matthew J.; Hyvärinen, Matti; Aukee, Pauliina; Tammelin, Tuija; Sipilä, Sarianna; Kovanen, Vuokko; Kujala, Urho M.; Laakkonen, Eija K. (Frontiers Media, 2019)Cardiovascular disease (CVD) is the primary cause of mortality in women in developed countries. CVD risk rises with age, yet for women there is a rapid increase in CVD risk that occurs after the onset of menopause. This ...