Näytä suppeat kuvailutiedot

dc.contributor.authorKallionpää, Roope A.
dc.contributor.authorJohansson, Edvard
dc.contributor.authorBöckerman, Petri
dc.contributor.authorPeltonen, Juha
dc.contributor.authorPeltonen, Sirkku
dc.date.accessioned2023-08-24T09:55:49Z
dc.date.available2023-08-24T09:55:49Z
dc.date.issued2024
dc.identifier.citationKallionpää, R. A., Johansson, E., Böckerman, P., Peltonen, J., & Peltonen, S. (2024). The contribution of morbidity and unemployment for the reduced labor market participation of individuals with neurofibromatosis 1 in Finland. <i>European Journal of Human Genetics</i>, <i>32</i>(1), 83-90. <a href="https://doi.org/10.1038/s41431-023-01426-5" target="_blank">https://doi.org/10.1038/s41431-023-01426-5</a>
dc.identifier.otherCONVID_184093620
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/88680
dc.description.abstractNeurofibromatosis 1 (NF1) is a multisystem disorder associated with, for example, a high risk for cancer, a variety of behavioral and cognitive deficits, low educational attainment and decreased income. We now examined the labor market participation of individuals with NF1. We analyzed the numbers of days of work, unemployment, and sickness allowance among 742 Finnish individuals with NF1 aged 20–59 years using nationwide register data from Statistics Finland and the Social Insurance Institution of Finland. The individuals with NF1 were compared with a control cohort of 8716 individuals matched with age, sex, and the area of residence. Individuals with NF1 had a significantly lower number of working days per year than the controls (rate ratio [RR] 0.93, 95% CI 0.91–0.95). Unemployment (RR 1.79, 95% CI 1.58–2.02), and sickness absence (RR 1.44, 95% CI 1.25–1.67) were more frequent in the NF1 than in the control group. The causes of sickness allowances were highly concordant with the previously reported morbidity profile of NF1 including neoplasms, cardiovascular disease, mental and behavioral diseases, and neurological diseases. In conclusion, NF1 significantly interferes with labor market participation via both unemployment and morbidity. Unemployment seems to cause more days of not working than sickness absence.en
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherS. Karger
dc.relation.ispartofseriesEuropean Journal of Human Genetics
dc.rightsCC BY 4.0
dc.titleThe contribution of morbidity and unemployment for the reduced labor market participation of individuals with neurofibromatosis 1 in Finland
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202308244770
dc.contributor.laitosKauppakorkeakoulufi
dc.contributor.laitosSchool of Business and Economicsen
dc.contributor.oppiaineEmpirical Microeconomicsfi
dc.contributor.oppiaineTaloustiedefi
dc.contributor.oppiainePäätöksentekoa tukeva taloustiede ja talouden kilpailukyky (painoala)fi
dc.contributor.oppiaineEmpirical Microeconomicsen
dc.contributor.oppiaineEconomicsen
dc.contributor.oppiainePolicy-Relevant Economics and Competitiveness of Economy (focus area)en
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange83-90
dc.relation.issn1018-4813
dc.relation.numberinseries1
dc.relation.volume32
dc.type.versionpublishedVersion
dc.rights.copyright© The Author(s) 2023
dc.rights.accesslevelopenAccessfi
dc.subject.ysotyömarkkina-asema
dc.subject.ysosairauspoissaolot
dc.subject.ysohermoston taudit
dc.subject.ysoneurofibromatoosi
dc.subject.ysotyöttömyys
dc.subject.ysosairastavuus
dc.subject.ysoneurodegeneratiiviset sairaudet
dc.subject.ysotyömarkkinat
dc.subject.ysosairaudet
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p23554
jyx.subject.urihttp://www.yso.fi/onto/yso/p24142
jyx.subject.urihttp://www.yso.fi/onto/yso/p295
jyx.subject.urihttp://www.yso.fi/onto/yso/p6082
jyx.subject.urihttp://www.yso.fi/onto/yso/p11571
jyx.subject.urihttp://www.yso.fi/onto/yso/p3556
jyx.subject.urihttp://www.yso.fi/onto/yso/p28721
jyx.subject.urihttp://www.yso.fi/onto/yso/p8831
jyx.subject.urihttp://www.yso.fi/onto/yso/p2633
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/
dc.relation.doi10.1038/s41431-023-01426-5
jyx.fundinginformationThe study was funded with grants from the Turku University Hospital and the Cancer Foundation Finland. This work is generated within the European Reference Network on Genetic Tumour Risk Syndromes (ERN GENTURIS)—Project ID No 739547. ERN GENTURIS is partly co-funded by the European Union within the framework of the Third Health Programme “ERN-2016—Framework Partnership Agreement 2017–2021”. The study was funded with grants from the Turku University Hospital and the Cancer Foundation Finland. Open Access funding provided by University of Turku (UTU) including Turku University Central Hospital.
dc.type.okmA1


Aineistoon kuuluvat tiedostot

Thumbnail

Aineisto kuuluu seuraaviin kokoelmiin

Näytä suppeat kuvailutiedot

CC BY 4.0
Ellei muuten mainita, aineiston lisenssi on CC BY 4.0