Show simple item record

dc.contributor.authorYousri, Amal
dc.contributor.authorEl-Faham, Ayman
dc.contributor.authorHaukka, Matti
dc.contributor.authorAyoup, Mohammed Salah
dc.contributor.authorIsmail, Magda M. F.
dc.contributor.authorEl Menofy, Nagwan G.
dc.contributor.authorSoliman, Saied M.
dc.contributor.authorÖhrström, Lars
dc.contributor.authorBarakat, Assem
dc.contributor.authorAbu-Youssef, Morsy A. M.
dc.date.accessioned2023-05-31T06:04:56Z
dc.date.available2023-05-31T06:04:56Z
dc.date.issued2023
dc.identifier.citationYousri, A., El-Faham, A., Haukka, M., Ayoup, M. S., Ismail, M. M. F., El Menofy, N. G., Soliman, S. M., Öhrström, L., Barakat, A., & Abu-Youssef, M. A. M. (2023). A Novel Na(I) Coordination Complex with s-Triazine Pincer Ligand : Synthesis, X-ray Structure, Hirshfeld Analysis, and Antimicrobial Activity. <i>Crystals</i>, <i>13</i>(6), Article 890. <a href="https://doi.org/10.3390/cryst13060890" target="_blank">https://doi.org/10.3390/cryst13060890</a>
dc.identifier.otherCONVID_183355298
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/87321
dc.description.abstractThe pincer ligand 2,4-bis(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-1,3,5-triazine (bpmt) was used to synthesize the novel [Na(bpmt)2][AuCl4] complex through the self-assembly method. In this complex, the Na(I) ion is hexa-coordinated with two tridentate N-pincer ligands (bpmt). The two bpmt ligand units are meridionally coordinated to Na(I) via one short Na-N(s-triazine) and two slightly longer Na-N(pyrazole) bonds, resulting in a distorted octahedral geometry around the Na(I) ion. In the coordinated bpmt ligand, the s-triazine core is not found to be coplanar with the two pyrazole moieties. Additionally, the two bpmt units are strongly twisted from one another by 64.94°. Based on Hirshfeld investigations, the H···H (53.4%) interactions have a significant role in controlling the supramolecular arrangement of the [Na(bpmt)2][AuCl4] complex. In addition, the Cl···H (12.2%), C···H (11.5%), N···H (9.3%), and O···H (4.9%) interactions are significant. Antimicrobial investigations revealed that the [Na(bpmt)2][AuCl4] complex has promising antibacterial and antifungal activities. The [Na(bpmt)2][AuCl4] complex showed enhanced antibacterial activity for the majority of the studied gram-positive and gram-negative bacteria compared to the free bpmt (MIC = 62.5–125 µg/mL vs. MIC = 62.5–500 µg/mL, respectively) and Amoxicillin (MIC > 500 µg/mL) as a positive control. Additionally, the [Na(bpmt)2][AuCl4] complex had better antifungal efficacy (MIC = 125 µg/mL) against C. albicans compared to bpmt (MIC = 500 µg/mL).en
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherMDPI AG
dc.relation.ispartofseriesCrystals
dc.rightsCC BY 4.0
dc.subject.otherNa(I) coordination complex
dc.subject.others-triazine pincer ligand
dc.subject.otherX-ray
dc.subject.otherHirshfeld surface
dc.subject.otherantimicrobial activity
dc.titleA Novel Na(I) Coordination Complex with s-Triazine Pincer Ligand : Synthesis, X-ray Structure, Hirshfeld Analysis, and Antimicrobial Activity
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202305313376
dc.contributor.laitosKemian laitosfi
dc.contributor.laitosDepartment of Chemistryen
dc.contributor.oppiaineEpäorgaaninen kemiafi
dc.contributor.oppiaineEpäorgaaninen ja analyyttinen kemiafi
dc.contributor.oppiaineInorganic Chemistryen
dc.contributor.oppiaineInorganic and Analytical Chemistryen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.relation.issn2073-4352
dc.relation.numberinseries6
dc.relation.volume13
dc.type.versionpublishedVersion
dc.rights.copyright© 2023 by the authors. Licensee MDPI, Basel, Switzerland
dc.rights.accesslevelopenAccessfi
dc.subject.ysokompleksiyhdisteet
dc.subject.ysokemiallinen synteesi
dc.subject.ysoantimikrobiset yhdisteet
dc.subject.ysonatrium
dc.subject.ysoröntgenkristallografia
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p30190
jyx.subject.urihttp://www.yso.fi/onto/yso/p8468
jyx.subject.urihttp://www.yso.fi/onto/yso/p21949
jyx.subject.urihttp://www.yso.fi/onto/yso/p8414
jyx.subject.urihttp://www.yso.fi/onto/yso/p29058
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/
dc.relation.doi10.3390/cryst13060890
jyx.fundinginformationThe authors would like to extend their sincere appreciation to the Researchers Supporting Project (RSP2023R64), King Saud University, Riyadh, Saudi Arabia.
dc.type.okmA1


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

CC BY 4.0
Except where otherwise noted, this item's license is described as CC BY 4.0