dc.contributor.author | Waselius, Tomi | |
dc.contributor.author | Xu, Weiyong | |
dc.contributor.author | Sparre, Julia Isabella | |
dc.contributor.author | Penttonen, Markku | |
dc.contributor.author | Nokia, Miriam S. | |
dc.date.accessioned | 2022-02-18T11:34:11Z | |
dc.date.available | 2022-02-18T11:34:11Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Waselius, T., Xu, W., Sparre, J. I., Penttonen, M., & Nokia, M. S. (2022). Cardiac cycle and respiration phase affect responses to the conditioned stimulus in young adults trained in trace eyeblink conditioning. <i>Journal of Neurophysiology</i>, <i>127</i>(3), 767-775. <a href="https://doi.org/10.1152/jn.00298.2021" target="_blank">https://doi.org/10.1152/jn.00298.2021</a> | |
dc.identifier.other | CONVID_104202059 | |
dc.identifier.uri | https://jyx.jyu.fi/handle/123456789/79846 | |
dc.description.abstract | Rhythms of breathing and heartbeat are linked to each other as well as to rhythms of the brain. Our recent studies suggest that presenting the conditioned stimulus during expiration or during the diastolic phase of the cardiac cycle facilitates neural processing of that stimulus and improves learning an eyeblink classical conditioning task. To date, it has not been examined whether utilizing information from both respiration and cardiac cycle phases simultaneously allows even more efficient modulation of learning. Here we studied whether the timing of the conditioned stimulus to different cardiorespiratory rhythm phase combinations affects learning trace eyeblink conditioning in healthy young adults. The results were consistent with previous reports: Timing the conditioned stimulus to diastole during expiration was more beneficial for learning than timing it to systole during inspiration. Cardiac cycle phase seemed to explain most of this variation in learning at the behavioral level. Brain evoked potentials (N1) elicited by the conditioned stimulus and recorded using electroencephalogram were larger when the conditioned stimulus was presented to diastole during expiration than when it was presented to systole during inspiration. Breathing phase explained the variation in the N1 amplitude. To conclude, our findings suggest that non-invasive monitoring of bodily rhythms combined with closed-loop control of stimulation can be used to promote learning in humans. The next step will be to test if performance can also be improved in humans with compromised cognitive ability, such as in older people with memory impairments. | en |
dc.format.mimetype | application/pdf | |
dc.language.iso | eng | |
dc.publisher | American Physiological Society | |
dc.relation.ispartofseries | Journal of Neurophysiology | |
dc.rights | In Copyright | |
dc.subject.other | hengitys | |
dc.subject.other | sydämen syke | |
dc.subject.other | herätevaste | |
dc.subject.other | oppiminen | |
dc.subject.other | breathing | |
dc.subject.other | heartbeat | |
dc.subject.other | event-related potential | |
dc.subject.other | learning | |
dc.title | Cardiac cycle and respiration phase affect responses to the conditioned stimulus in young adults trained in trace eyeblink conditioning | |
dc.type | article | |
dc.identifier.urn | URN:NBN:fi:jyu-202202181573 | |
dc.contributor.laitos | Psykologian laitos | fi |
dc.contributor.laitos | Department of Psychology | en |
dc.contributor.oppiaine | Monitieteinen aivotutkimuskeskus | fi |
dc.contributor.oppiaine | Psykologia | fi |
dc.contributor.oppiaine | Hyvinvoinnin tutkimuksen yhteisö | fi |
dc.contributor.oppiaine | Käyttäytymisen muutos, hyvinvointi ja terveys elämänkulussa | fi |
dc.contributor.oppiaine | Aivojen muutokset elinkaaren aikana | fi |
dc.contributor.oppiaine | Centre for Interdisciplinary Brain Research | en |
dc.contributor.oppiaine | Psychology | en |
dc.contributor.oppiaine | School of Wellbeing | en |
dc.contributor.oppiaine | Behaviour change, health, and well-being across the lifespan | en |
dc.contributor.oppiaine | Brain changes across the life-span | en |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | |
dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | |
dc.description.reviewstatus | peerReviewed | |
dc.format.pagerange | 767-775 | |
dc.relation.issn | 0022-3077 | |
dc.relation.numberinseries | 3 | |
dc.relation.volume | 127 | |
dc.type.version | acceptedVersion | |
dc.rights.copyright | © 2022, Journal of Neurophysiology | |
dc.rights.accesslevel | openAccess | fi |
dc.relation.grantnumber | 321522 | |
dc.subject.yso | syke | |
dc.subject.yso | oppiminen | |
dc.subject.yso | hengitys | |
dc.subject.yso | ehdollistuminen | |
dc.subject.yso | psykofysiologia | |
dc.subject.yso | kognitiiviset prosessit | |
dc.format.content | fulltext | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p3751 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p2945 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p5640 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p2942 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p7543 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p5283 | |
dc.rights.url | http://rightsstatements.org/page/InC/1.0/?language=en | |
dc.relation.doi | 10.1152/jn.00298.2021 | |
dc.relation.funder | Research Council of Finland | en |
dc.relation.funder | Suomen Akatemia | fi |
jyx.fundingprogram | Academy Project, AoF | en |
jyx.fundingprogram | Akatemiahanke, SA | fi |
jyx.fundinginformation | The work was supported by the Academy of Finland grant number 321522 to MSN. | |
dc.type.okm | A1 | |