Isolation and characterization of Yersinia phage fMtkYen3-01
Goladze, S., Patpatia, S., Tuomala, H., Ylänne, M., Gachechiladze, N., de Oliveira Patricio, D., Skurnik, M., & Sundberg, L.-R. (2024). Isolation and characterization of Yersinia phage fMtkYen3-01. Archives of Virology, 169, Article 226. https://doi.org/10.1007/s00705-024-06149-6
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Archives of VirologyDate
2024Copyright
© The Author(s) 2024
Yersinia enterocolitica causes yersiniosis, the third most common gastrointestinal infection in humans throughout Europe. The emergence of multidrug resistance and the lack of effective new antibiotics have drawn attention to phage therapy as a treatment option. Here, we report the complete genome sequence of phage fMtkYen3-01, which infects Y. enterocolitica serotype O:3 strains. This phage has a genome 40,415 bp in length with 45.1% GC content and 49 predicted genes. fMtkYen3-01 infected 9.5% of the 42 Y. enterocolitica strains tested and showed stability at 25–40 °C, as well as pH 5.0–10.0. These results suggest the therapeutic potential of this phage.
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Springer NatureISSN Search the Publication Forum
0304-8608Keywords
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https://converis.jyu.fi/converis/portal/detail/Publication/243572497
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Research Council of FinlandFunding program(s)
Academy Project, AoFAdditional information about funding
Open Access funding provided by University of Jyväskylä (JYU). This research was supported by Shota Rustaveli National Science Foundation of Georgia (SRNSFG) (grant number PHDF-21-2176), the Finnish National Agency for Education (EDUFI) [TM-21-11539] (for S.G.), and the Research Council of Finland (#346772, for L.-R.S.).License
Except where otherwise noted, this item's license is described as CC BY 4.0