Combined intermittent hypoxic exposure at rest and continuous hypoxic training can maintain elevated hemoglobin mass after a hypoxic camp
Peltonen, J. E., Leppävuori, A., Lehtonen, E., Mikkonen, R. S., Kettunen, O., Nummela, A., Ohtonen, O., Gagnon, D. D., Wehrlin, J. P., Wilber, R. L., & Linnamo, V. (2024). Combined intermittent hypoxic exposure at rest and continuous hypoxic training can maintain elevated hemoglobin mass after a hypoxic camp. Journal of Applied Physiology, In Press. https://doi.org/10.1152/japplphysiol.00017.2024
Published in
Journal of Applied PhysiologyAuthors
Date
2024Access restrictions
Embargoed until: 2025-07-05Request copy from author
Copyright
© 2024 American Physiological Society
Athletes use hypoxic living and training to increase hemoglobin mass (Hbmass), but Hbmass declines rapidly upon return to sea level. We investigated whether Intermittent Hypoxic Exposure (IHE) + Continuous Hypoxic Training (CHT) after return to sea level maintained elevated Hbmass, and if changes in Hbmass were transferred to changes in maximal oxygen uptake (V̇O2max) and exercise performance. Hbmass was measured in 58 endurance athletes before (PRE), after (POST1), and 30 days after (POST2) a 27 ± 4-day training camp in hypoxia (n=44, HYP) or at sea level (n=14, SL). After return to sea level, 22 athletes included IHE (2 h rest) + CHT (1 h training) into their training every third day for one month (HYPIHE+CHT), whereas the other 22 HYP athletes were not exposed to IHE or CHT (HYPSL). Hbmass increased from PRE to POST1 in both HYPIHE+CHT (4.4 ± 0.7%, mean ± SEM) and HYPSL (4.1 ± 0.6%) (both p<0.001). Compared to PRE, Hbmass at POST2 remained 4.2 ± 0.8% higher in HYPIHE+CHT (p<0.001) and1.9 ± 0.5% higher in HYPSL (p=0.023), indicating a significant difference between the groups (p=0.002). In SL, no significant changes were observed in Hbmass with mean alterations between -0.5% and 0.4%. V̇O2max and time to exhaustion during an incremental treadmill test (n=35) were elevated from PRE to POST2 only in HYPIHE+CHT (5.8 ± 1.2% and 5.4 ± 1.4%, respectively, both p<0.001). IHE+CHT possesses the potential to mitigate the typical decline in Hbmass commonly observed during the initial weeks after return to sea level.
...
Publisher
American Physiological SocietyISSN Search the Publication Forum
8750-7587Keywords
Publication in research information system
https://converis.jyu.fi/converis/portal/detail/Publication/221089820
Metadata
Show full item recordCollections
- Liikuntatieteiden tiedekunta [3148]
Additional information about funding
This study was financially supported as follows: 1) Helsinki: Ministry of Education and Culture, Finland (OKM/128/626/2021; OKM/39/626/2022; OKM/67/626/2023) and Urheiluopistosäätiö (12/10/2021); 2) Vuokatti: Joint Authority of Kainuu region (ERDF, 308764), Ministry of Education and Culture (OKM/3/626/2022).License
Related items
Showing items with similar title or keywords.
-
Impact of Energy Availability, Health and Sex on Hemoglobin Mass Responses Following Live-High–Train-High Altitude Training in Elite Female and Male Distance Athletes
Heikura, Ida A.; Burke, Louise M.; Bergland, Dan; Uusitalo, Arja L. T.; Mero, Antti; Stellingwerff, Trent (Human Kinetics, 2018)Purpose: The authors investigated the effects of sex, energy availability (EA), and health status on the change in hemoglobin mass (ΔHbmass) in elite endurance athletes over ∼3–4 wk of live-high–train-high altitude training ... -
Hemoglobin mass and performance responses during 4 weeks of normobaric “live high–train low and high”
Kettunen, Oona; Leppävuori, Antti; Mikkonen, Ritva; Peltonen, Juha E.; Nummela, Ari; Wikström, Bettina; Linnamo, Vesa (Wiley, 2023)Purpose To investigate whether 4 weeks of normobaric “live high–train low and high” (LHTLH) causes different hematological, cardiorespiratory, and sea-level performance changes compared to living and training in normoxia ... -
Rautastatuksen yhteys maksimaaliseen hapenottokykyyn ja suorituskykyyn naiskestävyysurheilijoilla
Kinnunen, Veera (2024)Rauta on ihmiselle välttämätön hivenaine, sillä se osallistuu elimistössä hapenkuljetukseen sekä energia-aineenvaihduntaan. Raudan merkitys korostuu urheilijoilla, sillä heikentyneen rautastatuksen on osoitettu laskevan ... -
Kolmen viikon live high – train low -harjoitusjakson vaikutukset hemoglobiinimassaan, maksimihapenottoon ja maksimikestävyyssuorituskykyyn hiihtolajien urheilijoilla
Virtanen, Heta (2024)Tässä tutkielmassa oli tarkoitus selvittää kolmen viikon live high – train low -harjoitusjakson mahdollisia vaikutuksia hemoglobiinimassaan, maksimihapenottokykyyn sekä maksimikestävyyssuorituskykyyn hiihtolajien urheilijoilla. ... -
Aptamer-Embedded DNA Origami Cage for Detecting (Glycated) Hemoglobin with a Surface Plasmon Resonance Sensor
Duanghathaipornsuk, Surachet; Shen, Boxuan; Cameron, Brent D.; Ijäs, Heini; Linko, Veikko; Kostiainen, Mauri A.; Kim, Dong-Shik (Elsevier, 2020)DNA origami-based cages functionalized with aptamer motifs, were used to detect hemoglobin and glycated hemoglobin. The binding between the cages and hemoglobin was monitored using a surface plasmon resonance (SPR) sensor. ...