Associations of cardiorespiratory fitness, body composition, and blood pressure with arterial stiffness in adolescent, young adult, and middle-aged women
Haapala, E. A., Lee, E., Karppinen, J., Skog, H., Valtonen, M., Kujala, U. M., Laukkanen, J. A., Ihalainen, J. K., & Laakkonen, E. K. (2022). Associations of cardiorespiratory fitness, body composition, and blood pressure with arterial stiffness in adolescent, young adult, and middle-aged women. Scientific Reports, 12, Article 21378. https://doi.org/10.1038/s41598-022-25795-x
Published inScientific Reports
DisciplineGerontologia ja kansanterveysBiomekaniikkaLiikuntafysiologiaLiikuntalääketiedeGerontology and Public HealthBiomechanicsExercise PhysiologySports and Exercise Medicine
© The Author(s) 2022
Few studies have investigated whether higher cardiorespiratory fitness (CRF) or favourable body composition are related to lower arterial stiffness in women. We therefore investigated the associations of CRF, body fat percentage (BF%), fat free mass index (FFMI), and mean arterial pressure (MAP) with arterial stiffness in 146 women aged 16–58 years. CRF was assessed by a maximal exercise test with respiratory gas analysis either on a cycle ergometer or a treadmill. Aortic pulse wave velocity (PWVao), augmentation index (AIx%), and MAP were assessed by a non-invasive oscillometric device and BF% and FFMI by a bioelectrical impedance or DXA device. CRF was inversely associated with PWVao (β = − 0.004, 95% CI − 0.005 to − 0.002) and AIx% (β = − 0.075, 95% CI − 0.102 to − 0.048) and these associations remained similar after adjustment for BF% or MAP, but not after the adjustment for age. FFMI was inversely associated with PWVao (β = − 0.010, 95% CI − 0.019 to − 0.002) and MAP directly associated with PWVao (β = 0.005, 95% CI 0.003 to 0.006) and AIx% (β = 0.092, 95% CI 0.069 to 0.116) and the associations with PWVao also remained after further adjustments for BF% and age. In conclusion, a higher FFMI and a lower MAP were independently associated with lower arterial stiffness. ...
PublisherNature Publishing Group
Publication in research information system
MetadataShow full item record
- Liikuntatieteiden tiedekunta 
Related funder(s)Academy of Finland
Funding program(s)Research costs of Academy Research Fellow, AoF; Academy Project, AoF; Academy Research Fellow, AoF; Foundation
Additional information about fundingThis study was supported by the Academy of Finland Grants 309504, 314181, 335249, and 330281 to EKL, by the Finnish Foundation for Cardiovascular Research and the Juho Vainio Foundation to EAH, and by Urheiluopistosäätiö Grant 20190110 to JKI.
Showing items with similar title or keywords.
Associations of cardiorespiratory fitness, physical activity, and BMI with arterial health in middle‐aged men and women Haapala, Eero; Lee, E., Laukkanen, J. A. (Wiley Periodicals; American Physiological Society and the Physiological Society, 2020)We investigated the associations of cardiorespiratory fitness (CRF), physical activity (PA) with regard to aerobic and resistance training, and body mass index (BMI) with pulse wave velocity (PWV) and augmentation index ...
Cross-sectional associations between cardiorespiratory fitness and NMR-derived metabolic biomarkers in children : the PANIC study Haapala, Eero A.; Leppänen, Marja H.; Lehti, Maarit; Lintu, Niina; Tompuri, Tuomo; Viitasalo, Anna; Schwab, Ursula; Lakka, Timo A. (Frontiers Media SA, 2022)Objective: Cardiorespiratory fitness has been inversely associated with cardiovascular risk across the lifespan. Some studies in adults suggest that higher cardiorespiratory fitness is associated with cardioprotective ...
Arterial Stiffness and Its Relationship to Cardiorespiratory Fitness in Children and Young Adults with a Fontan Circulation Noortman, Laurien C. M.; Haapala, Eero; Takken, Tim (Springer New York LLC, 2019)There are no previous studies on arterial stiffness and its associations with cardiorespiratory fitness in young Fontan patients. Therefore, we examined the arterial stiffness and its relationship to cardiorespiratory ...
Association between resting blood pressure and maximal blood pressure response to exercise and arterial health Joensuu, Henri (2022)We investigated the longitudinal associations of blood pressure, cardiorespiratory fitness, and arterial stiffness among children. Arterial stiffening has been repeatedly shown to be a cardiovascular mortality predictor ...
Associations of Cardiorespiratory Fitness and Adiposity With Arterial Stiffness and Arterial Dilatation Capacity in Response to a Bout of Exercise in Children Agbaje, Andrew O.; Haapala, Eero; Lintu, Niina; Viitasalo, Anna; Väistö, Juuso; Khan, Sohaib; Veijalainen, Aapo; Tompuri, Tuomo; Laitinen, Tomi; Lakka, Timo A. (Human Kinetics, Inc., 2019)Purpose: To investigate the associations of directly measured peak oxygen uptake (V˙O2peak) and body fat percentage (BF%) with arterial stiffness and arterial dilatation capacity in children. Methods: Findings are based ...