Effects of 26 weeks plyometric and dynamic strength training and estrogen replacement therapy on isometric muscle strength of postmenopausal women
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Circulating miR-21, miR-146a and Fas ligand respond to postmenopausal estrogen-based hormone replacement therapy : A study with monozygotic twin pairs
Kangas, Reeta; Pöllänen, Eija; Rippo, Maria Rita; Lanzarini, Catia; Prattichizzo, Francesco; Niskala, Paula; Jylhävä, Juulia; Sipilä, Sarianna; Kaprio, Jaakko; Procopio, Antonio Domenico; Capri, Miriam; Franceschi, Claudio; Olivieri, Fabiola; Kovanen, Vuokko (Elsevier Ireland Ltd., 2014)Biological aging is associated with physiological deteriorations and its’ remodeling, which are partly due to changes in the hormonal profile. MicroRNAs are known to post-transcriptionally regulate various cellular processes ... -
Influence of long-term postmenopausal hormone replacement therapy on estimated structural bone strength: A study in discordant monozygotic twins.
Mikkola, Tuija; Heinonen, Ari; Kovanen, Vuokko; Cheng, Sulin; Kujala, Urho; Suominen, Harri; Alén, Markku; Puolakka, Jukka; Ankarberg-Lindgren, Carina; Ronkainen, Paula; Koskenvuo, Markku; Kaprio, Jaakko; Rantanen, Taina; Sipilä, Sarianna (Wiley Blackwell, 2011)Although postmenopausal hormone-replacement therapy (HRT) is known to prevent fractures, knowledge on the influence of long-term HRT on bone strength and its determinants other than areal bone mineral density is scarce. ... -
Aging and serum exomiR content in women-effects of estrogenic hormone replacement therapy
Kangas, Reeta; Törmäkangas, Timo; Fey, Vidal; Pursiheimo, Juha; Miinalainen, Ilkka; Alen, Markku; Kaprio, Jaakko; Sipilä, Sarianna; Säämänen, Anna-Marja; Kovanen, Vuokko; Laakkonen, Eija (Nature Publishing Group, 2017)Exosomes participate in intercellular messaging by transporting bioactive lipid-, protein- and RNA-molecules and -complexes. The contents of the exosomes reflect the physiological status of an individual making exosomes ... -
Regulation of gene expression and steroidogenesis in skeletal muscle of postmenopausal women : with emphasis on the effects of hormone replacement and power training
Pöllänen, Eija (University of Jyväskylä, 2011) -
Power training and postmenopausal hormone therapy affect transcriptional control of specific co-regulated gene clusters in skeletal muscle
Pöllänen, Eija; Fey, Vidal; Törmäkangas, Timo; Ronkainen, Paula; Taaffe, Dennis; Takala, Timo; Koskinen, Satu; Cheng, Sulin; Puolakka, Jukka; Kujala, Urho; Suominen, Harri; Sipilä, Sarianna; Kovanen, Vuokko (Springer, 2010)At the moment, there is no clear molecular explanation for the steeper decline in muscle performance after menopause or the mechanisms of counteractive treatments. The goal of this genome-wide study was to identify the ...