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dc.contributor.authorHaapala, Eero A.
dc.contributor.authorSjöros, Tanja
dc.contributor.authorLaine, Saara
dc.contributor.authorGarthwaite, Taru
dc.contributor.authorKallio, Petri
dc.contributor.authorSaarenhovi, Maria
dc.contributor.authorVähä-Ypyä, Henri
dc.contributor.authorLöyttyniemi, Eliisa
dc.contributor.authorSievänen, Harri
dc.contributor.authorHouttu, Noora
dc.contributor.authorLaitinen, Kirsi
dc.contributor.authorKalliokoski, Kari
dc.contributor.authorKnuuti, Juhani
dc.contributor.authorVasankari, Tommi
dc.contributor.authorHeinonen, Ilkka H. A.
dc.date.accessioned2022-02-28T09:23:08Z
dc.date.available2022-02-28T09:23:08Z
dc.date.issued2022
dc.identifier.citationHaapala, E. A., Sjöros, T., Laine, S., Garthwaite, T., Kallio, P., Saarenhovi, M., Vähä-Ypyä, H., Löyttyniemi, E., Sievänen, H., Houttu, N., Laitinen, K., Kalliokoski, K., Knuuti, J., Vasankari, T., & Heinonen, I. H. A. (2022). Association between cardiorespiratory fitness and metabolic health in overweight and obese adults. <i>Journal of Sports Medicine and Physical Fitness</i>, <i>62</i>(11), 1526-1533. <a href="https://doi.org/10.23736/S0022-4707.21.13234-7" target="_blank">https://doi.org/10.23736/S0022-4707.21.13234-7</a>
dc.identifier.otherCONVID_102930486
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/79981
dc.description.abstractBACKGROUND: Cardiorespiratory fitness (CRF) has been inversely associated with insulin resistance and clustering of cardiometabolic risk factors among overweight and obese individuals. However, most previous studies have scaled CRF by body mass (BM) possibly inflating the association between CRF and cardiometabolic health. We investigated the associations of peak oxygen uptake (V̇ O2peak) and peak power output (Wpeak) scaled either by BM-1, fat free mass (FFM-1), or by allometric methods with individual cardiometabolic risk factors and clustering of cardiometabolic risk factors in 55 overweight or obese adults with metabolic syndrome. METHODS: V̇ O2peak and Wpeak were assessed by a maximal cycle ergometer exercise test. FFM was measured by air displacement plethysmograph and glucose, insulin, HbA1c, triglycerides, and total, LDL, and HDL cholesterol from fasting blood samples. HOMA-IR and metabolic syndrome score (MetS) were computed. RESULTS: V̇ O2peak and Wpeak scaled by BM-1 were inversely associated with insulin (β=-0.404 to -0.372, 95% CI=-0.704 to -0.048), HOMA-IR (β=-0.442 to -0.440, 95% CI=-0.762 to -0.117), and MetS (β=-0.474 to -0.463, 95% CI’s=-0.798 to -0.127). Other measures of CRF were not associated with cardiometabolic risk factors. CONCLUSIONS: Our results suggest that using BM-1 as a scaling factor confounds the associations between CRF and cardiometabolic risk in overweight/obese adults with the metabolic syndrome.en
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherEdizioni Minerva Medica
dc.relation.ispartofseriesJournal of Sports Medicine and Physical Fitness
dc.rightsIn Copyright
dc.subject.otheraerobic fitness
dc.subject.othermetabolic syndrome
dc.subject.otherinsulin resistance
dc.subject.otherallometry
dc.titleAssociation between cardiorespiratory fitness and metabolic health in overweight and obese adults
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202202281705
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.contributor.oppiaineBiomekaniikkafi
dc.contributor.oppiaineLiikuntalääketiedefi
dc.contributor.oppiaineBiomechanicsen
dc.contributor.oppiaineSports and Exercise Medicineen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange1526-1533
dc.relation.issn0022-4707
dc.relation.numberinseries11
dc.relation.volume62
dc.type.versionacceptedVersion
dc.rights.copyright© 2021 Edizioni Minerva Medica
dc.rights.accesslevelopenAccessfi
dc.subject.ysofyysinen kunto
dc.subject.ysolihavuus
dc.subject.ysoaerobinen suorituskyky
dc.subject.ysometabolinen oireyhtymä
dc.subject.ysoylipaino
dc.subject.ysoinsuliiniresistenssi
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p7384
jyx.subject.urihttp://www.yso.fi/onto/yso/p823
jyx.subject.urihttp://www.yso.fi/onto/yso/p24946
jyx.subject.urihttp://www.yso.fi/onto/yso/p6238
jyx.subject.urihttp://www.yso.fi/onto/yso/p826
jyx.subject.urihttp://www.yso.fi/onto/yso/p22290
dc.rights.urlhttp://rightsstatements.org/page/InC/1.0/?language=en
dc.relation.doi10.23736/S0022-4707.21.13234-7
dc.type.okmA1


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